Results 81 to 90 of about 1,868,246 (184)

Comparison of intestinal histopathological changes following teclistamab, BCMA‐directed CAR T, CD19‐directed CAR T and rituximab therapies

Histopathology, EarlyView.
This is a retrospective review of intestinal tract biopsies from patients treated with various cellular immunotherapies (BCMA and CD19‐directed CAR T, teclistamab and rituximab therapies). We found distinct but overlapping histologic patterns across treatment groups, with lamina propria plasma cell depletion, crypt apoptotic bodies and active ...
Olivia J Leung, Esther Baranov, Isairis Peralta Valerio, Robin Collingwood, Natalie Respond, Don Siegel, Pooja Devi, Kristen M. Stashek   +7 more
wiley   +1 more source

Epidemiology of Clostridium Difficile Infection [PDF]

Deutsches Ärzteblatt international, 2015
According to L¨bbert et al., the incidence of Clostridium difficile infection (CDI) in Germany is 5 to 20 cases per 100 000 persons (1). It can be assumed that this figure is much too low. An ecological study based on routine data identified a total of 9874 cases hospitalized because of CDI, as well as further 26 341 cases with CDI as a concomitant ...
openaire   +2 more sources

Postelectroacupuncture Fecal Microbiota Transplantation (post‐EA FMT) Regulates Gastrointestinal Hormones in Functional Dyspepsia Rats Is Associated With Modulation of the Intestinal Microbiota‐Bile Acid Metabolic Pathway

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background Electroacupuncture (EA) reshapes intestinal flora; whether post‐EA fecal microbiota transplantation (post‐EA FMT) regulates gastrointestinal hormones via the gut microbiota–bile acid (BA) pathway remains unclear. Methods Sham EA (SEA) served as control. Gastrointestinal hormones/motility were assessed post‐EA.
Yong‐Li Han, Dong‐Fang Shang, Juli Tang, Dong‐Dong Yu, Liang‐Yu Zhang, Jing Zhou, Qing‐Bo Wang   +6 more
wiley   +1 more source

Investigation into the mobile genetic elements of Clostridium difficile [PDF]

, 2013
Clostridium difficile is a pathogenic bacterium that can colonise both humans and various animals. Toxin production leads to clinical symptoms ranging from mild to severe diarrhoea and can result in potentially fatal pseudomembranous colitis.
Brouwer, MSM
core  

Treatment of Clostridium difficile infection [PDF]

Journal of Antimicrobial Chemotherapy, 1998
The treatment options for Clostridium difficile infection remain limited, although promising agents are currently being assessed. Metronidazole is the first-line drug of choice for those patients requiring specific anti-C. difficile treatment. Much of the interest in alternative therapies has centred on the difficult management issues posed by patients
openaire   +2 more sources

Periodontitis and Inflammatory Bowel Diseases: Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This review aims to provide a conceptual framework for understanding the mechanistic interplay between periodontitis and IBD, with a particular emphasis on the microbial and immunological crosstalk linking the oral cavity and the gastrointestinal tract.
Ana Paula V. Colombo, Adriana M. de Oliveira, Nobuhiko Kamada, Sho Kitamoto   +3 more
wiley   +1 more source

Case report of clostridium difficile infection after rectal resection with ileostomy

World Journal of Surgical Oncology
Colorectal cancer is the third most common cancer worldwide, with high incidence and mortality rates. Surgical resection is the primary treatment for rectal cancer.
Hongwei Guo, Huiyuan Jiang, Haiyi Liu
doaj   +1 more source

Topological, Functional, and Phylogenetic Analysis of the Cell Division Site Selection Protein MinJ of Bacillus subtilis

Molecular Microbiology, EarlyView.
MinJ is a nine‐pass transmembrane protein with a cytoplasmic PDZ domain. The PDZ domain, while required for division, is dispensable for localization, and deletion of the transmembrane segments 6 and 7 results in a hyper‐minicell phenotype. ABSTRACT The Min system disassembles FtsZ‐rings after septation in Bacillus subtilis and is localized to the ...
Kehinde O. Adebiyi, Laura C. Lastra, Jane H. Joncha, Sadie B. Ruesewald, Stephen C. Jacobson, Daniel B. Kearns   +5 more
wiley   +1 more source

Clostridium difficile Infection, Colorado and the Northwestern United States, 2007

Emerging Infectious Diseases, 2012
To determine the incidence of Clostridium difficile infection during 2007, we examined infection in adult inpatient and outpatient members of a managed-care organization. Incidence was 14.9 C. difficile infections per 10,000 patient-years.
Jennifer L. Kuntz, Eric S. Johnson, Marsha A. Raebel, Amanda F. Petrik, Xiuhai Yang, Micah L. Thorp, Steven J. Spindel, Nancy Neil, David H. Smith   +8 more
doaj   +1 more source

Microbiome and Metabolomics in Obesity: Advances in Understanding and Interventions Across the Lifespan

Obesity Reviews, EarlyView.
ABSTRACT Obesity arises from intertwined and reciprocal diet‐microbiome‐host pathways that reshape energy balance, insulin sensitivity, and inflammation. This review synthesizes mechanistic links between microbial functions and metabolic control, charts lifestyle‐related lifecourse dynamics from birth to older age, examines how GLP‐1‐based therapies ...
Ioanna Panagiota Kalafati, David Krongauz, Alice Bosco, Antonio Noto, Cristina Piras, Maria Kafyra, Angelica Dessì, Matteo Mauri, Luigi Atzori, Adina Weinberger, Vassilios Fanos, George V. Dedoussis, on behalf of the BETTER4U consortium   +12 more
wiley   +1 more source