Results 81 to 90 of about 34,415 (160)

Urologic Bacteriome: The Hero or the Villain in Prostate Cancer Onset, Progression, and Treatment?

Medicinal Research Reviews, EarlyView.
ABSTRACT Prostate cancer (PCa) is the second most frequently diagnosed cancer in men worldwide and the fifth leading cause of cancer‐related mortality, presenting urgent unmet clinical needs in diagnosis and treatment. The recognition of the microbiome as a key factor in human health has prompted numerous studies, revealing an exciting new approach to ...
Lara R. S. Fonseca, Mariana Feijó, Cátia V. Vaz, Bruno J. Pereira, Sandra Laurentino, Ana Palmeira‐de‐Oliveira, Sílvia Socorro   +6 more
wiley   +1 more source

Effects of Clostridium perfringens iota toxin in the small intestine of mice [PDF]

, 2017
Iota toxin is a binary toxin solely produced by Clostridium perfringens type E strains, and is structurally related to CDT from C. difficile and CST from C. spiroforme.
Bruzzone, Octavio Augusto, Cangelosi, Adriana, Dailoff, Gabriela Cecilia, Díaz Carrasco, Juan María, Fernandez Miyakawa, Mariano Enrique, Geoghegan, Patricia, Leiva, Carlos Leónidas, Redondo, Enzo Alejandro, Redondo, Leandro Martin   +8 more
core   +1 more source

Correlation Between Gut Microbiota, Metabolites, and Diabetic Complications: A Two‐Sample Mendelian Randomization Study

Medicine Advances, EarlyView.
Fang et al. demonstrate a significant causal relationship among gut microbiota, gut metabolites, and diabetic complications, highlighting a biological link underlying mechanisms of diabetic vascular diseases. These findings provide important implications for future therapeutic strategy and risk prediction.
Jiaxi Fang, Leilei Zhai, Chan Huang, Liqin Li, Yong Wang, Jiaojiao Fan, Wei Zhou   +6 more
wiley   +1 more source

The Expanding Landscape of Microbiota Medicine: Indications, Therapeutic Modalities, and the Path Towards Integrative Microbiome‐Targeting Healthcare

Microbiota Medicine Research, EarlyView.
ABSTRACT The growing recognition of the microbiome's role in human health has propelled the emergence of microbiota medicine—a new discipline integrating microbiology, multi‐omics, and clinical science. Advances in sequencing, data integration, and interventions such as fecal microbiota transplantation (FMT) have transitioned the field from ...
Min Dai, Yisha Lin, Renyou Gan, Xiaotao Shen, Shin Young Park, Sunjae Lee, Qi Su   +6 more
wiley   +1 more source

Para-cresol production by Clostridium difficile affects microbial diversity and membrane integrity of Gram-negative bacteria [PDF]

, 2018
Clostridium difficile is a Gram-positive spore-forming anaerobe and a major cause of antibiotic-associated diarrhoea. Disruption of the commensal microbiota, such as through treatment with broad-spectrum antibiotics, is a critical precursor for ...
Baines, Simon D, Bianconi, Irene, Cutting, Simon M, Dawson, Lisa F, Harrison, Mark A, Hong, Huynh A, Kaur, Harparkash, Letertre, Marine P M, Nasher, Fauzy, Passmore, Ian J, Preston, Mark D, Swann, Jonathan R, Wren, Brendan W   +12 more
core   +6 more sources

Open Versus Hybrid and Total Minimally Invasive Transthoracic Ivor Lewis Esophagectomy Following Neoadjuvant FLOT Chemotherapy: An Australian and New Zealand Cohort Study

World Journal of Surgery, EarlyView.
Retrospective analysis of transthoracic oesophagectomies undertaken between 2017 and 2022 following neoadjuvant FLOT chemotherapy from 22 ANZ centers. The primary endpoint was the rate of major (Clavien‐Dindo grade ≥ 3) postoperative complication.
Brendan Desmond, Maneesha De Silva, Darren J. Wong, David I. Watson, Cuong P. Duong, Tim Bright, Ahmad Aly, Margaret Lee, Kevin Chan, Garett Smith, David L. Chan, Neil Merrett, Sivakumar Gananadha, Yick Ho Lam, Harsh Kanhere, Mark Smithers, Michael Bozin, Matthew Read, Krinal Mori, Mary‐Ann Johnson, Enoch Wong, Sarah A. Martin, Geraldine Ooi, Yahya Al‐Habbal, Chon Hann Liew, Robert Bohmer, Jurstine Daruwalla, Mo Ballal, Rukshan Ranjan, Andrew D. MacCormick, Sharon Pattison, Nicholas Evennett, Jason Robertson, James Tan, Alexandra Gordon, Simon Bann, David S. Liu, SPACE‐FLOT ANZ Investigators   +37 more
wiley   +1 more source

Vonoprazan pharmacokinetics and effects on gastric pH following administration to fed and fasted horses

Equine Veterinary Journal, EarlyView.
Abstract Background Current treatment options for equine gastric ulcer syndrome (EGUS), such as omeprazole—a proton pump inhibitor (PPI)—have notable limitations, including the need for administration on an empty stomach. Potassium‐competitive acid blockers (P‐CABs), such as vonoprazan, are a newer class of acid suppressants that offer several ...
Camilo J. Morales, Benjamin W. Sykes, Daniel S. McKemie, Philip H. Kass, Heather K. Knych   +4 more
wiley   +1 more source

Laboratory data as a quality indicator of health-care-associated infections in England. [PDF]

, 2018
Routine diagnostic laboratory results, e.g. numbers of meticillin-resistant Staphylococcus aureus (MRSA) bacteraemias, have been used as health-care-associated infection quality indicators for decades. The English health-care-associated infection quality
Jeyaratnam, D, Planche, T
core   +1 more source

Systemic effects of sunlight: 10‐year review of cardiovascular, infection and cancer outcomes

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This review highlights the systemic effects of sunlight and ultraviolet radiation. While UV radiation exposure has known cutaneous risks including photoaging and skin cancer, evidence suggests potential associations with reduced all‐cause mortality, improved infectious disease outcomes and reduced blood pressure.
Jasira A. Ziglar, Rebecca L. Quiñonez, Lydiah Fridah M. Mpyisi, Indermeet Kohli, Yolanda Gilaberte, Henry W. Lim   +5 more
wiley   +1 more source

Role of the microbiome, probiotics, and 'dysbiosis therapy' in critical illness. [PDF]

, 2016
Purpose of reviewLoss of 'health-promoting' microbes and overgrowth of pathogenic bacteria (dysbiosis) in ICU is believed to contribute to nosocomial infections, sepsis, and organ failure (multiple organ dysfunction syndrome).
Knight, Rob, McDonald, Daniel, Wischmeyer, Paul E   +2 more
core   +2 more sources