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Clostridium difficile infection [PDF]

open access: yesThe Lancet, 2008
Clostridium difficile is a Gram-positive, anaerobic, spore-producing anaerobe [1] responsible for approximately 50–70% of gastrointestinal infections in hospitalized patients [2, 3]. An episode of C. difficile infection (CDI) is defined as a clinical picture compatible with CDI (i.
Kuipers, Ernst, Surawicz, CM
  +8 more sources

Clostridium difficile Infection [PDF]

open access: yesMedical Clinics of North America, 2013
Clostridium difficile is emerging as a common cause of infectious diarrhea. Incidence has increased dramatically since 2000, associated with a new strain that features both increased toxin production and increased resistance to antibiotics. For patients with mild to moderate disease, oral metronidazole is usually the first choice of treatment, and ...
Christopher L, Knight   +1 more
  +7 more sources

Clostridium difficile infection [PDF]

open access: yesNature Reviews Disease Primers, 2016
Infection of the colon with the Gram-positive bacterium Clostridium difficile is potentially life threatening, especially in elderly people and in patients who have dysbiosis of the gut microbiota following antimicrobial drug exposure. C. difficile is the leading cause of health-care-associated infective diarrhoea. The life cycle of C.
Smits, W.K.   +4 more
openaire   +8 more sources

Clostridium difficile infection

open access: yesAutopsy and Case Reports, 2014
Clostridium difficile infection (CDI) is a significant and increasing medical problem, surpassing methicillin-resistant Staphylococcus aureus as the most common hospital-onset or facility-associated infection, and a key element in the challenging battle against hospital-acquired infections.
Stephen A. Geller   +1 more
  +7 more sources

Clostridium paraputrificum: An atypical and rare case of septic arthritis mimicking an acute sickle cell crisis

open access: yesIDCases, 2021
Clostridium paraputrificum is an extremely rare species and constitutes only 1% of all clostridium infections in literature. Septic arthritis from Clostridium paraputrificum is even less documented, and currently there is only one known case report ...
Jordan Ciuro   +3 more
doaj   +1 more source

Clostridium difficile Infection

open access: yesClinical and Translational Gastroenterology, 2015
Clostridium difficile infection (CDI) affects a broad population and has become so widespread the Centers for Disease Control and Prevention rated C. difficile as an urgent threat in 2013.1, 2 Recent basic-science research has focused on understanding the pathogenesis of the disease and alterations in the microbiome causing susceptibility.
Dale N. Gerding, Vincent B. Young
  +6 more sources

Clostridium difficile infection [PDF]

open access: yesNursing Older People, 2010
Clostridium difficile can be cultured from the stool of 3 per cent of healthy adults but most people remain asymptomatic. Clinical disease develops when normal gut flora is disrupted, usually by antibiotic exposure, thereby creating conditions that favour C. difficile proliferation in the colon. Gastrointestinal diseases associated with C.
Latisha, Heinlen, Jimmy D, Ballard
openaire   +4 more sources

Clostridium difficile: An Important Opportunistic Pathogen in Healthcare-Associated Infections

open access: yesEDIS, 2018
Healthcare-associated infections are infections that patients can get while receiving medical treatment in a healthcare facility. One opportunistic pathogen, Clostridium difficile, has been getting more attention in recent years because of its ...
Soohyoun Ahn, Amarat Simonne
doaj   +5 more sources

Diarrhoea caused by Clostridium difficile in patients with postoperative subhepatic abscess [PDF]

open access: yesVojnosanitetski Pregled, 2008
Background. Toxigenic strains of Clostridium difficile in the majority of cases cause disease of the intestinal tract of hospitalized patients. For a long time, Clostridium difficile was considered to produce both types of toxins (A+/B+ strain), however,
Stojanović Predrag, Kocić Branislava
doaj   +1 more source

Outcomes of intrahospital antimicrobial stewardship programs related to prevention of Clostridium difficile infection outbreaks [PDF]

open access: yesMedicinski Glasnik, 2018
Aim To synthesize evidence about the influence of individual antimicrobial stewardship programs (ASP) related to the prevention of Clostridium difficile (C. difficile) infection on primary and secondary outcomes.
Biljana Mijović   +5 more
doaj   +1 more source

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