Results 21 to 30 of about 108,867 (254)

The Recent Emergence of Clostridium difficile Infection in Romanian Hospitals is Associated with a High Prevalence of Polymerase Chain Reaction Ribotype 027

Balkan Medical Journal, 2018
Aims: To investigate the epidemiology of Clostridium difficile infection in Romanian hospitals. Methods: A survey was conducted at nine hospitals throughout Romania between November 2013 and February 2014.
Gabriel Adrian Popescu, Roxana Serban, Adriana Pistol, Andreea Niculcea, Daniela Lemeni, Ioana Sabina Macovei, Daniela Tălăpan, Alexandru Rafila, Dragoş Florea   +8 more
doaj   +1 more source

Bacteriemia por Clostridium sordellii en paciente con neoplasia gastrointestinal. Reporte de caso y revisión de literatura

Infectio, 2020
Clostridium sordellii bacteriemia is infrequent and usually comes from infections of gynecological and puerperal etiology, with mortality near 70%. There are few tools for rapid and timely diagnosis.
Juan Bravo-Ojeda
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Managing High Exudate Wounds: Improvised Negative Pressure Wound Therapy in Clostridial Infection

Journal of Indian Association of Pediatric Surgeons
We report a rare and life-threatening case of pediatric gas gangrene caused by Clostridium septicum following an intramuscular injection. The child presented with severe pain and blisters over the left gluteal region.
M. G. Jayakrishna, Nanditha Ananthakrishnan, Asha Jyothi Penugonda, Beula Subashini Panchatcharam, Susan Jehangir   +4 more
doaj   +1 more source

The role of a sequencing-based clinical intestinal screening test in patients at high-risk for Clostridium difficile and other pathogens: a case report

Journal of Medical Case Reports, 2019
Background Hospitalization and antibiotic treatment can put patients at high risk for Clostridium difficile infection, where a disturbance of the gut microbiome allows for Clostridium difficile proliferation and associated symptoms, including mild ...
Maureen Hitschfeld, Elena Tovar, Sarah Gupta, Elisabeth M. Bik, Christina Palmer, Michael C. Hoaglin, Daniel E. Almonacid, Jessica Richman, Zachary S. Apte   +8 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Association of tcdB PCR Cycle Threshold with Toxin Antigen Positivity and Clinical Severity in Clostridioides difficile Infection

Korean Journal of Clinical Laboratory Science
Various methods are used to diagnose and evaluate the severity of a Clostridioides difficile infection (CDI). Among them, the correlation between the tcdB gene PCR cycle threshold (Ct) values and toxin antigen detection is a key area of research.
Chan Kyu KIM, Ho-Keun CHOI
doaj   +1 more source

CLOSTRIDIUM DIFFICILE ASSOCIATED DISEASE IN THE NEUROINTENSIVECARE UNIT.

Frontiers in Neurology, 2013
. BACKGROUND- Critically ill patients are at high risk for acquiring Clostridium difficile infection. The aim of this study was to investigate the prevalence, severity and outcome of Neurointensive Care Unit (NICU) acquired Clostridium difficile ...
Swagata eTripathy, Priya eNair, Michael eRothburn, Michael eRothburn   +3 more
doaj   +1 more source

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

Advanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu, Hongjie Dai, Xiaocui Zhong, Qibin Li, Hui Yuan, Yang Yang, Daiyong Huang, Lei Zhang, Rui Ran, Tian He, Yuanzhi Huang, Silas Villas‐Boas, Sergey Tumanov, Richard D. Cannon, Boris Novakovic, Richard Saffery, Yuhao Zhang, Xiaojing Dong, Ting‐Li Han   +18 more
wiley   +1 more source

Structural and Functional Siderophore Remodeling by Enzymatic Delipidation

Angewandte Chemie, EarlyView.
A surprising functional switch in bacterial siderophores was discovered through genome mining and the analysis of environmental and pathogenic Pandoraea species. Pandorachelin B, a lipocyclopeptide that promotes swarming motility, is cleaved by a specialized acylase, yielding a ring‐contracted, homodetic cyclopeptide, pandorachelin A, which exhibits ...
Elena Herzog, Keishi Ishida, Evelyn M. Molloy, Ron Hermenau, Kirstin Scherlach, Christian Hertweck   +5 more
wiley   +2 more sources