Results 221 to 230 of about 165,772 (340)

Aptamer Engineering: Strategies for Discovering Functional Nucleic Acids for Next‐Generation Diagnostics and Biosensing

open access: yesAdvanced Science, Volume 13, Issue 2, 9 January 2026.
The advent of aptamers has highlighted their potential as alternatives to antibodies, overcoming limitations of structural instability and production cost. However, conventional approaches such as SELEX remain slow and labor‐intensive. This review examines recent advances in aptamer engineering, emphasizing in vitro and AI‐driven in silico strategies ...
John V. L. Nguyen   +5 more
wiley   +1 more source

Impact of Low Preoperative Prognostic Immune Nutritional Index on Survival and Postoperative Infectious Complications in Patients With Colorectal Cancer

open access: yesAnnals of Gastroenterological Surgery, Volume 10, Issue 1, Page 154-166, January 2026.
This study investigated the prognostic value of the preoperative prognostic immune nutritional index (PINI) in colorectal cancer. A low preoperative PINI was significantly associated with both poor oncological outcomes and an increased risk of postoperative infectious complications.
Shinji Yamashita   +9 more
wiley   +1 more source

MOESM3 of Community-acquired infection with hypervirulent Clostridium difficile isolates that carry different toxin and antibiotic resistance loci: a case report

open access: gold, 2017
Marina Muñoz   +5 more
openalex   +1 more source

Comparing Prophylactic Administration of Sulbactam/Ampicillin Versus Cefmetazole for Prevention of Perineal Wound Infection Following Abdominoperineal Resection for Rectal Cancer: A Multicenter Randomized Controlled Trial

open access: yesAnnals of Gastroenterological Surgery, Volume 10, Issue 1, Page 15-24, January 2026.
This prospective randomized trial demonstrated that a 4‐day regimen of sulbactam/ampicillin significantly reduced the incidence of perineal wound infection (PWI) following abdominoperineal resection compared to a 1‐day cefmetazole regimen. This simple approach to antibiotic selection may be beneficial for preventing PWI.
Akitoshi Nankaku   +12 more
wiley   +1 more source

Woman With Vomiting and Fever. [PDF]

open access: yesJ Am Coll Emerg Physicians Open
Sun J, Zhao A, Li X, Liu Y.
europepmc   +1 more source

Exploring Fecal Microbiota Transplantation: Potential Benefits, Associated Risks, and Challenges in Cancer Treatment

open access: yesCancer Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Background Fecal microbiota transplantation (FMT) has emerged as a groundbreaking strategy for modulating the gut microbiome and improving cancer treatment outcomes. This review synthesizes the current evidence on the role of FMT in oncology, focusing on its potential to enhance the efficacy of immunotherapy, restore microbiome homeostasis ...
Aswathi Ramesh   +3 more
wiley   +1 more source

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