Results 301 to 310 of about 3,472,654 (379)

Pyroptosis in Peripheral Neuropathy: From Molecular Mechanisms to Therapeutic Targeting

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
Pyroptosis is a key inflammatory cell death pathway in peripheral neuropathy, with opposing roles: it perpetuates neuropathic pain but can be induced to kill neuroblastoma cells. This review consolidates mechanistic understanding and therapeutic strategies, arguing for a shift from disease‐centric to target‐centric treatment approaches to improve ...
Jinhuan Wei   +11 more
wiley   +1 more source

Impact of targeted interventions on healthcare-acquired infection prevention and control of Clostridium difficile infections. [PDF]

open access: yesAntimicrob Resist Infect Control
Zhang S   +8 more
europepmc   +1 more source

Baseline multi‐omics signatures could predict therapeutic response to neoadjuvant anti‐PD‐1 immunochemotherapy in non‐small‐cell lung cancer

open access: yesClinical and Translational Medicine, Volume 16, Issue 1, January 2026.
Overview of study design. Metagenomic and plasma/fecal metabolomic studies were performed in 44 NSCLC patients who underwent neoadjuvant tislelizumab therapy plus platinum ‐ based doublet chemotherapy. Abstract Background Neoadjuvant anti‐programmed cell death 1 (PD‐1) immunochemotherapy has shown promising efficiency in the treatment of early‐stage ...
Ailing Cao   +11 more
wiley   +1 more source

Bifidobacterium longum subsp. longum CCFM1375 Mitigates Chronic Kidney Disease Progression via Gut Microbiota Modulation and Gut Barrier Restoration

open access: yesFood Frontiers, Volume 7, Issue 1, January 2026.
(1) Bifidobacterium longum subsp. longum CCFM1375 restored gut barrier integrity by upregulating ZO‐1/ZO‐2 and suppressing IL‐6/TNF‐α, thereby reducing serum LPS and improving creatinine/BUN levels. (2) Reshaped gut microbiota: enriched beneficial species (Faecalibaculum rodentium, Asaccharobacter celatus, Adlercreutzia equolifaciens) while suppressing
Hongchao Wang   +11 more
wiley   +1 more source

Recent Advances in the Bioactive Compounds of Prunes (Prunus domestica L.) and Their Health Benefits

open access: yesFood Frontiers, Volume 7, Issue 1, January 2026.
Prunes (Prunus domestica L.) are a functional food rich in diverse bioactive compounds, including polyphenols (such as chlorogenic acid and anthocyanins), polysaccharides, and sorbitol.This review comprehensively synthesizes current research on the nutritional composition and biological activities of prunes, highlighting their multifaceted health ...
Luyang Han   +10 more
wiley   +1 more source

Liver-Microbiome Crosstalk Mediates the Protective Effects of Artemisinin in Clostridium perfringens Models. [PDF]

open access: yesMicrob Biotechnol
Han H   +12 more
europepmc   +1 more source

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