Pyroptosis in Peripheral Neuropathy: From Molecular Mechanisms to Therapeutic Targeting
Pyroptosis is a key inflammatory cell death pathway in peripheral neuropathy, with opposing roles: it perpetuates neuropathic pain but can be induced to kill neuroblastoma cells. This review consolidates mechanistic understanding and therapeutic strategies, arguing for a shift from disease‐centric to target‐centric treatment approaches to improve ...
Jinhuan Wei +11 more
wiley +1 more source
Impact of targeted interventions on healthcare-acquired infection prevention and control of Clostridium difficile infections. [PDF]
Zhang S +8 more
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Overview of study design. Metagenomic and plasma/fecal metabolomic studies were performed in 44 NSCLC patients who underwent neoadjuvant tislelizumab therapy plus platinum ‐ based doublet chemotherapy. Abstract Background Neoadjuvant anti‐programmed cell death 1 (PD‐1) immunochemotherapy has shown promising efficiency in the treatment of early‐stage ...
Ailing Cao +11 more
wiley +1 more source
The role of gut microbiota in the formation of IBD, a typical chronic intestinal inflammatory disease. [PDF]
Chen J.
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THE POWER OF POOP: FECAL MICROBIOTA TRANSPLANTATION FOR CLOSTRIDIUM DIFFICILE INFECTION.
Michael B. Edmond
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(1) Bifidobacterium longum subsp. longum CCFM1375 restored gut barrier integrity by upregulating ZO‐1/ZO‐2 and suppressing IL‐6/TNF‐α, thereby reducing serum LPS and improving creatinine/BUN levels. (2) Reshaped gut microbiota: enriched beneficial species (Faecalibaculum rodentium, Asaccharobacter celatus, Adlercreutzia equolifaciens) while suppressing
Hongchao Wang +11 more
wiley +1 more source
<i>Clostridium difficile</i> Colonization in Oncologic Patients Undergoing Major Abdominopelvic Surgery: To Treat or Not to Treat? An Observational Study with Propensity Score Analysis. [PDF]
Lunca S +5 more
europepmc +1 more source
Recent Advances in the Bioactive Compounds of Prunes (Prunus domestica L.) and Their Health Benefits
Prunes (Prunus domestica L.) are a functional food rich in diverse bioactive compounds, including polyphenols (such as chlorogenic acid and anthocyanins), polysaccharides, and sorbitol.This review comprehensively synthesizes current research on the nutritional composition and biological activities of prunes, highlighting their multifaceted health ...
Luyang Han +10 more
wiley +1 more source
Liver-Microbiome Crosstalk Mediates the Protective Effects of Artemisinin in Clostridium perfringens Models. [PDF]
Han H +12 more
europepmc +1 more source

