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2025 ACVIM Forum Research Abstract Program
Journal of Veterinary Internal Medicine, Volume 39, Issue 6, November/December 2025.
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Clostridium difficile infection
Medicina Clínica (English Edition), 2017Clostridium difficile infection (CDI) is the main cause of nosocomial diarrhea in industrialized countries and the source of a growing number of cases of diarrhea in the community. The outbreak of the hypervirulent strain belonging to ribotype 027 has increased the incidence and severity of CDI in some countries.
Luis Alcalá Hernández +2 more
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Clostridium difficileInfection
New England Journal of Medicine, 2015This article reviews the pathogenesis, epidemiology, diagnosis, and treatment of this nosocomial and potentially fatal infectious diarrhea, as well as the associated risk factors. New treatments include fecal microbiota transplantation for disease that is resistant to vancomycin.
Sam K Sharma +2 more
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Clostridium difficile Infection
Critical Reviews in Clinical Laboratory Sciences, 1996The spore-forming anaerobe Clostridium difficile has become a serious enteropathogen. Changes in the composition of natural intestinal flora, mainly due to antibiotic therapy, permit its colonization of, and multiplication in, the colon. The disease is caused by (entero)toxin A and (cyto)toxin B, and infection ranges from asymptomatic carrier state and
Dieter H. M. Gröschel, B. Toye
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CLOSTRIDIUM SORDELLI INFECTION
The Journal of Trauma: Injury, Infection, and Critical Care, 1975A case of human Clostridium sordelli soft tissue infection is presented. Analysis of this patient's course led to the use of a mouse experimental model for examination of this organism's potential for toxin production. Data thus obtained correlated with that seen in this instance of human infection, indicates that the lethal effects of this organism ...
John H. Davis +4 more
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CNS Infection with Clostridium septicum
Scandinavian Journal of Infectious Diseases, 2000We present an unusual case of Clostridium septicum brain infection in a 72-yr-old woman who had no underlying malignant disease. The infection spread from a localized sit to the CNS causing gas formation. The patient died rapidly.
Dirks, C. +3 more
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Clostridium septicum Infections and Malignancy
JAMA: The Journal of the American Medical Association, 1969Twenty-eight patients had infections due to Clostridium septicum ; 21 of them had documented septicemia. A malignancy was present in 23 of the 27 patients for whom hospital records were available. In three, an intestinal tumor was found one to two months after C septicum was cultured.
Robert J. Alpern, V. R. Dowell
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Clostridium difficile Infection
Annual Review of Medicine, 1998Clostridium difficile infection is associated with broad-spectrum antibiotic therapy and is the most common cause of infectious diarrhea in hospital patients. Pathogenic strains of C. difficile produce two protein exotoxins, toxin A and toxin B, which cause colonic mucosal injury and inflammation. Infection may be asymptomatic, cause mild diarrhea, or
Ciaran P. Kelly, J T LaMont
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Clostridium difficile infection.
BMJ (Clinical research ed.), 2009Rangaiah and colleagues comment that currently used tests for Clostridium difficile toxin are not very sensitive.1 However, the specificity of these commercial assays also ranges from 97% to 99%, meaning that approximately 1-2 out of every 10 positive results using these kits are incorrect.2 False positive results are even more likely when testing ...
Tim Planche, Mark H. Wilcox
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