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Clostridium difficile Infection

Infectious Disease Clinics of North America, 2017
Clostridium difficile infection is a major health care challenge in terms of patient and economic consequences. For the patient, it is a morbid and sometimes a life-threatening iatrogenic complication of antibiotic treatment. In the United States, the provider's institution may face financial penalties, because the Centers for Disease Control and ...
Luis, Alcalá Hernández   +2 more
openaire   +4 more sources

Clostridium difficile Infection

Critical Reviews in Clinical Laboratory Sciences, 1996
The spore-forming anaerobe Clostridium difficile has become a serious enteropathogen. Changes in the composition of natural intestinal flora, mainly due to antibiotic therapy, permit its colonization of, and multiplication in, the colon. The disease is caused by (entero)toxin A and (cyto)toxin B, and infection ranges from asymptomatic carrier state and
Dieter H. M. Gröschel, B. Toye
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CLOSTRIDIUM SORDELLI INFECTION

The Journal of Trauma: Injury, Infection, and Critical Care, 1975
A case of human Clostridium sordelli soft tissue infection is presented. Analysis of this patient's course led to the use of a mouse experimental model for examination of this organism's potential for toxin production. Data thus obtained correlated with that seen in this instance of human infection, indicates that the lethal effects of this organism ...
D A, Browdie   +4 more
openaire   +2 more sources

Clostridium difficileInfection

New England Journal of Medicine, 2015
This article reviews the pathogenesis, epidemiology, diagnosis, and treatment of this nosocomial and potentially fatal infectious diarrhea, as well as the associated risk factors. New treatments include fecal microbiota transplantation for disease that is resistant to vancomycin.
Sam K, Sharma   +2 more
openaire   +7 more sources

Clostridium difficile infection

BMJ, 2009
Rangaiah and colleagues comment that currently used tests for Clostridium difficile toxin are not very sensitive.1 However, the specificity of these commercial assays also ranges from 97% to 99%, meaning that approximately 1-2 out of every 10 positive results using these kits are incorrect.2 False positive results are even more likely when testing ...
Mark H, Wilcox, Tim, Planche
openaire   +2 more sources

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