Results 81 to 90 of about 13,181 (300)

Exosome‐mediated gut–brain axis signaling in neurodegenerative diseases: Mechanisms, experimental evidence, and therapeutic perspectives—A narrative review

Animal Models and Experimental Medicine, EarlyView.
The gut–brain axis is a bidirectional communication network between the intestines and brain, mediated by gut microbiota and exosomes, that regulates neuroinflammation, protein aggregation, and neuronal health processes central to neurodegenerative diseases.
Waheeb Sami Aggad, Rakesh Ghosh, Hailah M. Almohaimeed, Zuhair M. Mohammedsaleh, Fayez M. Saleh, Amany I. Almars, S. Renuka Jyothi, Rajashree Panigrahi, Ajoy Kumer, Bikram Dhara   +9 more
wiley   +1 more source

Reducing the Risk of Severe Complications among Patients with Clostridium difficile Infection

Canadian Journal of Gastroenterology, 2011
BACKGROUND: The incidence and severity of Clostridium difficile infections are increasing, and there is a need to optimize the prevention of complicated disease.
Kamran Manek, Victoria Williams, Sandra Callery, Nick Daneman   +3 more
doaj   +1 more source

Clostridium difficile Infection, Colorado and the Northwestern United States, 2007

Emerging Infectious Diseases, 2012
To determine the incidence of Clostridium difficile infection during 2007, we examined infection in adult inpatient and outpatient members of a managed-care organization. Incidence was 14.9 C. difficile infections per 10,000 patient-years.
Jennifer L. Kuntz, Eric S. Johnson, Marsha A. Raebel, Amanda F. Petrik, Xiuhai Yang, Micah L. Thorp, Steven J. Spindel, Nancy Neil, David H. Smith   +8 more
doaj   +1 more source

Development and characterisation of an in vitro human gut model to study the biofilm mode of growth of clostridium difficile and the indigenous gut microbiota [PDF]

, 2013
Clostridium difficile infection (CDI) is associated with significant patient morbidity, mortality and financial burden. Until recently, antimicrobial treatment options were limited to metronidazole and vancomycin, but both agents are associated with ...
Crowther, Grace
core  

Clostridium species diversity in cattle

Ветеринария сегодня
Introduction. Clostridial infections, though relatively sporadic, are globally ubiquitous and specified by high mortality rates, resulting in substantial economic losses to agriculture.
P. N. Shastin, V. A. Savinov, A. I. Laishevtsev, E. D. Mandryka, E. A. Fabrikantova, A. V. Supova   +5 more
doaj   +1 more source

Clinical Risk Factors for Severe Clostridium difficile–associated Disease

Emerging Infectious Diseases, 2009
Identifying patients who are at high risk for severe Clostridium difficile–associated disease (CDAD) early in the course of their infection may help clinicians improve outcomes.
Timothy J. Henrich, Douglas Krakower, Asaf Bitton, Deborah S. Yokoe   +3 more
doaj   +1 more source

Probiotics in Clostridium difficile Infection [PDF]

Journal of Clinical Gastroenterology, 2011
Clostridium difficile infection (CDI) is one of the most prevalent nosocomial infections. A dramatic increase in the incidence and severity of CDI has been noted in the past decade. Current recommendations suggest metronidazole as first-line therapy in mild to moderately severe CDI and oral vancomycin in individuals with severe CDI, or when ...
Xi, Na, Ciaran, Kelly
openaire   +2 more sources

Clostridium difficile infection: review [PDF]

European Journal of Clinical Microbiology & Infectious Diseases, 2019
Clostridium difficile (C. difficile) is a Gram-positive, spore-forming, anaerobic bacillus, which is widely distributed in the intestinal tract of humans and animals and in the environment. In the last decade, the frequency and severity of C. difficile infection has been increasing worldwide to become one of the most common hospital-acquired infections.
Jacek Czepiel, Mirosław Dróżdż, Hanna Pituch, Ed J. Kuijper, William Perucki, Aleksandra Mielimonka, Sarah Goldman, Dorota Wultańska, Aleksander Garlicki, Grażyna Biesiada   +9 more
openaire   +6 more sources

Heat Stress and Gut Microbiome Dynamics in Poultry: Interplay, Consequences, and Mitigation Strategies

Animal Research and One Health, EarlyView.
Heat stress disrupts gut microbial balance in poultry, impairing nutrient absorption and immunity. This review outlines the interplay between thermal stress and microbiome dynamics and discusses integrative mitigation strategies, probiotics, phytogenics, cooling systems, and genetic adaptation to enhance poultry resilience.
O. E. Oke, A. I. Oni, O. A. Akosile, K. M. Oliyide, C. A. Ishola, M. O. Logunleko, O. A. Jimoh, C. P. Njoku, L. O. Fasasi, V. A. Uyanga   +9 more
wiley   +1 more source

Incidence and surveillance of infections from Clostridium difficile: the experience at the Galliera of Genoa in the three-year period 2004-2006

Microbiologia Medica, 2009
Introduction Clostridium difficile is a Gram-positive bacillus, anaerobic, sporogenous ,with oro-faecal transmission.The formation of the spores can persist in a long time, encouraging the transmission.
David Usiglio, Anna Maria Marrapodi, Mariangela Lanata, Paola Sansone, Marco Mori, Paola Fabbri, Nadia Cenderello, Mauro Nelli, Roberto Tramalloni, Maria Paola Crisalli, Giovanni Cassola   +10 more
doaj   +1 more source