Results 71 to 80 of about 7,548 (208)

The European Union One Health 2024 Zoonoses Report

EFSA Journal, Volume 23, Issue 12, December 2025.
Abstract This report by the European Food Safety Authority and the European Centre for Disease Prevention and Control presents the results of zoonoses monitoring and surveillance activities carried out in 2024 in 27 Member States (MSs), the United Kingdom (Northern Ireland) and eight non‐MSs, according to the Zoonoses Directive 2003/99/EC.
European Food Safety Authority (EFSA) | European Centre for Disease Prevention and Control (ECDC)
wiley   +1 more source

Isolation of Clostridium perfringens and C. difficile in crab-eating fox ( Cerdocyon thous - Linnaeus 1776) from Northeastern Brazil

Arquivo Brasileiro de Medicina Veterinária e Zootecnia
The aim of the present study was to isolate Clostridium perfringens and C. difficile in crab-eating fox (Cerdocyon thous) from Northeastern Brazil. Stool samples of 18 captive crab-eating foxes from four states of Northeastern Brazil (Alagoas, Bahia ...
J.C. Almeida, R.O.S. Silva, F.C.F. Lobato, R.A. Mota   +3 more
doaj   +1 more source

Endotoxin-Free Stx2B-C-CPE Vaccine and Its Optimized Adjuvant Regimen for Preventing Food Poisoning

Frontiers in Bioscience-Landmark, 2023
Background: Clostridium perfringens and Shiga toxin (Stx)-producing Escherichia coli (STEC) are common causes of food poisoning. We previously demonstrated the efficacy of Stx2B-C-CPE, a fusion protein of the C-terminal region of C.
Koji Hosomi, Atsushi Shimoyama, Atsushi Hinenoya, Noritoshi Hatanaka, Takafumi Noguchi, Hirotaka Ebina, Yoko Tojima, Mari Furuta, Masuo Kondoh, Hiroshi Kiyono, Shinji Yamasaki, Koichi Fukase, Jun Kunisawa   +12 more
doaj   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, Volume 599, Issue 22, Page 3208-3243, November 2025.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

The Circulation of Type F Clostridium perfringens among Humans, Sewage, and Ruditapes philippinarum (Asari Clams)

Pathogens, 2020
Clostridium perfringens is an important pathogen that is responsible for gastroenteritis; the causative agent for the symptoms is C. perfringens enterotoxin (CPE), which is mainly produced by type F C. perfringens.
Keita Yanagimoto, Kosei Uematsu, Takaya Yamagami, Eiji Haramoto   +3 more
doaj   +1 more source

Clostridium perfringens Associated with Foodborne Infections of Animal Origins: Insights into Prevalence, Antimicrobial Resistance, Toxin Genes Profiles, and Toxinotypes

Biology, 2022
Several food-poisoning outbreaks have been attributed to Clostridium perfringens (C. perfringens) worldwide. Despite that, this crisis was discussed in a few studies, and additional studies are urgently needed in this field.
Mahmoud M. Bendary, Marwa I. Abd El-Hamid, Reham M. El-Tarabili, Ahmed A. Hefny, Reem M. Algendy, Nahla A. Elzohairy, Mohammed M. Ghoneim, Mohammad M. Al-Sanea, Mohammed H. Nahari, Walaa H. Moustafa   +9 more
doaj   +1 more source

Clostridium perfringens Enterotoxin Interacts with Claudins via Electrostatic Attraction [PDF]

Journal of Biological Chemistry, 2010
Clostridium perfringens enterotoxin (CPE), a causative agent of food poisoning, is a pore-forming toxin disrupting the selective permeability of the plasma membrane of target cells, resulting in cell death. We previously identified claudin as the cell surface receptor for CPE. Claudin, a component of tight junctions, is a tetratransmembrane protein and
Jun, Kimura, Hiroyuki, Abe, Shigeki, Kamitani, Hirono, Toshima, Aya, Fukui, Masami, Miyake, Yoichi, Kamata, Yoshiko, Sugita-Konishi, Shigeki, Yamamoto, Yasuhiko, Horiguchi   +9 more
openaire   +2 more sources

NK Cell‐Derived Small Extracellular Vesicles Armed With CLDN4‐Targeting Peptides Potentiate Radiotherapy in Gastric Cancer

Journal of Extracellular Vesicles, Volume 14, Issue 11, November 2025.
ABSTRACT Gastric cancer (GC) persists as one of the most lethal malignancies globally, primarily due to late‐stage diagnosis, limited therapeutic targeting options, and inherent resistance to conventional therapies. While molecular profiling has advanced our understanding of GC, the development of effective delivery systems capable of precise tumour ...
Anqi Dong, Wenhao Shen, Xiaochun Shen, Shu Liu, Dongbao Li, Min Li, Minghui Li, Yan Ma, Jin Zhou, Lin Hu, Kai Yang   +10 more
wiley   +1 more source

Detection of Different Genotypes of Clostridium perfringens in Feces of Healthy Dairy Cattle from China using Real-Time Duplex PCR Assay [PDF]

Pakistan Veterinary Journal, 2011
Dual-labeled fluorescence hybridization probe-based multiplex quantitative real-time polymerase chain reaction (qPCR) assay was used for the detection of Clostridium perfringens toxin genes alpha (cpa), beta (cpb), iota (ia), epsilon (etx), beta2 (cpb2 ...
Guanghua Wang, Jizhang Zhou, Fuying Zheng, Guozhen Lin, Xiaoan Cao, Xiaowei Gong and Changqing Qiu*
doaj  

Humans as Reservoir for Enterotoxin Gene–carrying Clostridium perfringens Type A

Emerging Infectious Diseases, 2006
We found a prevalence of 18% for enterotoxin gene–carrying (cpe+) Clostridium perfringens in the feces of healthy food handlers by PCR and isolated the organism from 11 of 23 PCR-positive persons by using hydrophobic grid membrane filter-colony ...
Annamari Heikinheimo, Miia Lindström, Per Einar Granum, Hannu Korkeala   +3 more
doaj   +1 more source