ObjectiveEpidemiological investigation of a foodborne disease outbreak triggered by Clostridium perfringens in a school in Guiyang, traceability analysis of etiologic foods and pathogens, and exploration of the application of the new technology of whole ...
ZHANG Li +11 more
doaj +1 more source
Structure of the Claudin-binding Domain of Clostridium perfringens Enterotoxin [PDF]
Clostridium perfringens enterotoxin is a common cause of food-borne and antibiotic-associated diarrhea. The toxin's receptors on intestinal epithelial cells include claudin-3 and -4, members of a large family of tight junction proteins. Toxin-induced cytolytic pore formation requires residues in the NH(2)-terminal half, whereas residues near the COOH ...
Christina M, Van Itallie +4 more
openaire +2 more sources
Bacterial Extracellular Vesicles in Biomedical Research and Clinical Translation
Bacterial membrane vesicle biomedical applications. ABSTRACT Bacterial Extracellular Vesicles (bEVs) are lipid (single‐ or double‐bilayer) nanostructures secreted by virtually all bacteria that play fundamental roles in intercellular communication and have emerged as powerful, multifunctional tools in biomedicine. Their intrinsic ability to encapsulate
Alejandro Arce‐Rodríguez +2 more
wiley +1 more source
Clostridium perfringens type A isolates carrying the plasmid-borne enterotoxin gene (genotypes IS1151-cpe or IS1470-like-cpe) are a common cause of food poisonings. [PDF]
The prevalences of various genotypes of enterotoxin gene-carrying (cpe-positive) Clostridium perfringens type A in 24 different food poisoning outbreaks were 75% (chromosomal IS1470-cpe), 21% (plasmid-borne IS1470-like-cpe), and 4% (plasmid-borne IS1151 ...
Heikinheimo, Annamari +3 more
core +1 more source
Clostridium perfringens type F strains cause a common human foodborne illness and many cases of nonfoodborne human gastrointestinal diseases. Sporulation plays two critical roles during type F enteric disease.
John C. Freedman +3 more
doaj +1 more source
EHD4 and ASAP2 are critical negative regulators of the claudin‐5‐based endothelial barrier
Cell‐surface CLDN‐5 protein levels can be evaluated using a probe that can bind to the extracellular domains of CLDN‐5. A probe derived from Clostridium perfringens enterotoxin allows us to isolate cells with high CLDN‐5 protein levels from a knockout cell library.
Yosuke Hashimoto +8 more
wiley +1 more source
Comparison of toxicity neutralization-, ELISA- and PCR tests for typing of Clostridium perfringens and detection of the enterotoxin gene by PCR [PDF]
A polymerase chain reaction (PCR) was developed for the specific amplification of a part of each of the five Clostridium perfringens toxin genes: alpha (alpha), beta (beta), epsilon (epsilon), iota (iota), and enterotoxin (CPE).
Møller, Kristian, Ahrens, Peter
core +1 more source
Clostridium perfringens enterotoxin in antibiotic-associated diarrhea
Clostridium perfringens type A is associated with 5-20% cases of antibiotic-associated diarrhea (AAD) even though Clostridium difficile is implicated in the most severe cases. Fecal specimens from one hundred hospitalized patients, who developed diarrhea regardless of antibiotic intake and who were negative for C.
Vaishnavi Chetana, Kaur Sukhminderjit
openaire +3 more sources
Use of Dogs as an Assay for Clostridium perfringens Enterotoxin [PDF]
Three techniques for using the dog as an assay organism for Clostridium perfringens enterotoxin are described. These are believed to be more convenient than ligated ileal-loop procedures.
M L, Bartlett, H W, Walker, R, Ziprin
openaire +2 more sources
Risk assessment of the production of seaweed in the Netherlands; food safety and nature
Abstract Seaweed is seen as an important source of alternative proteins for a sustainable food system and food security. The cultivation of seaweed is therefore encouraged by the European Union (EU) and also by the Dutch government.In the Netherlands, seaweed is farmed on small scale in the Southwest Delta, the Wadden Sea and the North Sea. Despite the
S. M. Schrap +5 more
wiley +1 more source

