Results 121 to 130 of about 1,838,863 (339)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Closures and topological closures in quasi-discrete closure spaces
Applied Mathematics Letters, 2010 First for a finite set \(U\) and then an infinite set \(U\), the author establishes a one to one correspondence between the quasi-discrete closures on \(U\) and the reflexive relations on \(U\) and shows that \(S\) is the transitive closure of \(R\) if \(R\) and \(S\) are the relations determined by the closures cl and \(\text{cl}_T\) (the topological ...
openaire +2 more sources
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Biafra and the Aesthetics of Closure in the Third Generation Nigerian Novel [PDF]
Rupkatha Journal on Interdisciplinary Studies in Humanities, 2010 This paper examines the role of closure, or the lack thereof, in four contemporary Nigerian novels. Representative of the third wave of Nigerian literature, these narratives each deals with themes of trauma, identity and community affiliation in ...
Madhu Krishnan
doaj
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
The generalized drift flux approach: Identification of the void-drift closure law [PDF]
The main characteristics and the potential advantages of generalized drift flux models are presented. In particular it is stressed that the issue on the propagation properties and on the mathematical nature (hyperbolic or not) of the model and the ...
Boure, J. A.
core +1 more source
Transcatheter Closure of Patent Foramen Ovale Without an Implant [PDF]
, 2007 Horst Sievert +5 more
openalex +1 more source
FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
The Maxwell problem and the Chapman projection
Cubo, 2010 We study the large-time behavior of global smooth solutions to the Cauchy problem for hyperbolic regularization of conservation laws. An attracting manifold of special smooth global solutions is determined by the Chapman projection onto the phase space ...
V. V Palin, E. V Radkevich
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