Results 61 to 70 of about 957,959 (360)

Decommissioning and recommissioning a regional hospital in response to a COVID-19 outbreak

open access: yesRural and Remote Health, 2021
Context: The COVID-19 outbreak at the North West Regional Hospital (NWRH) site in Tasmania, Australia in April 2020 was both rapid and tragic. Within 10 days of identification of the first healthcare worker infection, both hospitals had closed, and all ...
Colleen Cheek   +4 more
doaj   +1 more source

Addressing the Consequences of School Closure Due to COVID‐19 on Children's Physical and Mental Well‐Being

open access: yesWorld Medical & Health Policy, 2020
Prolonged school closures are one of the most disruptive forces in the COVID‐19 era. School closures have upended life for children and families, and educators have been forced to determine how to provide distance learning.
Jessica A. Hoffman, Edward Miller
semanticscholar   +1 more source

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

open access: yesFEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li   +3 more
wiley   +1 more source

A detailed review of management of coronary perforations by gelfoam closure

open access: yesJournal of the Practice of Cardiovascular Sciences, 2021
We report a rare case of inadvertent distal small diagonal branch perforation noted postleft anterior descending coronary artery revascularization, rescued by Gelfoam closure in a 43-year diabetic male presenting with acute anterior wall ST elevated ...
Debasish Das   +3 more
doaj   +1 more source

Closures and topological closures in quasi-discrete closure spaces

open access: yesApplied Mathematics Letters, 2010
AbstractClosure space was introduced by Cech as a generalization of ordinary topology. In this work we establish a one to one correspondence between quasi-discrete closures and reflexive relations. We show that, in a quasi-discrete closure space, if a closure cl and its topological closure clT are respectively generated by relations R and S, then S is ...
openaire   +2 more sources

The impact of unplanned school closure on children’s social contact: rapid evidence review

open access: yesmedRxiv, 2020
Background Emergency school closures are often used as public health interventions during infectious disease outbreaks in an attempt to minimise the spread of infection.
S. Brooks   +6 more
semanticscholar   +1 more source

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

open access: yesFEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield   +3 more
wiley   +1 more source

Multimodal Computational Modeling of Visual Object Recognition Deficits but Intact Repetition Priming in Schizophrenia

open access: yesFrontiers in Psychiatry, 2020
The term perceptual closure refers to the neural processes responsible for “filling-in” missing information in the visual image under highly adverse viewing conditions such as fog or camouflage.
Pejman Sehatpour   +9 more
doaj   +1 more source

C‐mannosylation promotes ADAMTS1 activation and secretion in human testicular germ cell tumor NEC8 cells

open access: yesFEBS Letters, EarlyView.
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi   +5 more
wiley   +1 more source

The multidrug and toxin extrusion (MATE) transporter DTX51 antagonizes non‐cell‐autonomous HLS1–AMP1 signaling in a region‐specific manner

open access: yesFEBS Letters, EarlyView.
The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley   +1 more source

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