Results 51 to 60 of about 23,371 (266)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
For a set \(X\) and a complete residuated lattice \(L\), the author introduces and investigates graduated closure operators \(L^X\to L^X\), closure systems \(\subseteq L^X\) and systems of ``almost closed fuzzy sets'' \(L^X\to L\) in \(X\). He shows that they characterize each other and studies the relationship to fuzzy Galois connections.
openaire +2 more sources
The characterizations of upper approximation operators based on special coverings
In this paper, we discuss the approximation operators apr¯NS${\overline {apr} _{NS}}$ and apr¯S${\overline {apr} _S}$ which are based on NS(U) and S.
Wang Pei, Li Qingguo
doaj +1 more source
From torsion theories to closure operators and factorization systems [PDF]
Torsion theories are here extended to categories equipped with an ideal of 'null morphisms', or equivalently a full subcategory of 'null objects'. Instances of this extension include closure operators viewed as generalised torsion theories in a 'category
Marco Grandis, George Janelidze
doaj
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
On closure operators of Jonsson sets
The work is related to the study of the model-theoretic properties of Jonsson theories, which, generally speaking, are not complete. In the article, on the Boolean of Jonsson subsets of the semantic model of some fixed Jonsson theory, the concept of the
Olga Ulbrikht
doaj +1 more source
Classification of Multioperations of Rank 2 by E-precomplete Sets
In this paper multioperations defined on a two-element set and their closure operator based on composition operator and the equality predicate branching operator is considered. The composition operator is based on union of sets.
V.I. Panteleev, L.V. Ryabets
doaj +1 more source

