Results 61 to 70 of about 23,371 (266)
FEBS Letters, EarlyView.The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber +7 more
wiley +1 more source
FUZZY CLOSURE SYSTEMS AND FUZZY CLOSURE OPERATORS
Communications of the Korean Mathematical Society, 2004 Summary: We introduce fuzzy closure systems and fuzzy closure operators as extensions of closure systems and closure operators. We study relationships between fuzzy closure systems and fuzzy closure spaces. In particular, two families \(F(S)\) and \(F(C)\) of fuzzy closure systems and fuzzy closure operators on \(X\) are complete lattice isomorphic.
Kim, Yong Chan, Ko, Jung Mi
openaire +2 more sources
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Parametric Closed Classes of Hyperfunctions on Two-Element Set
Известия Иркутского государственного университета: Серия "Математика", 2016 One of the direction in discrete function's investigations is research of functional systems: the sets of functions and the sets of operators defined on this functions.
L. Ryabets
doaj
All about unambiguous polynomial closure [PDF]
TheoretiCSWe study a standard operator on classes of languages: unambiguous polynomial closure. We prove that for every class C of regular languages satisfying mild properties, the membership problem for its unambiguous polynomial closure UPol(C) reduces to the ...
Thomas Place, Marc Zeitoun
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
On the number of databases and closure operations
Theoretical Computer Science, 1991 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Gustav Burosch +4 more
openaire +1 more source