Results 61 to 70 of about 759,634 (294)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Axiomatic systems of Alexandrov spaces
Journal of Hebei University of Science and Technology, 2017 In order to study internel axiomatic systems and ordered features of Alexandrov spaces, with the help of some existed results in topology and locale theory, by restricting the related structures into Alexandrov setting, some equivalent descriptions are ...
Shanshan ZHANG, Fei LI, Wei YAO
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
On the Closure of Elliptic Wedge Operators [PDF]
Journal of Geometric Analysis, 2012 22 pages, improved ...
Gil, Juan B. +2 more
openaire +2 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
On closure operators of Jonsson sets
Қарағанды университетінің хабаршысы. Математика сериясыThe work is related to the study of the model-theoretic properties of Jonsson theories, which, generally speaking, are not complete. In the article, on the Boolean of Jonsson subsets of the semantic model of some fixed Jonsson theory, the concept of the
Olga Ulbrikht
doaj +1 more source
FUZZY CLOSURE SYSTEMS AND FUZZY CLOSURE OPERATORS
Communications of the Korean Mathematical Society, 2004 Summary: We introduce fuzzy closure systems and fuzzy closure operators as extensions of closure systems and closure operators. We study relationships between fuzzy closure systems and fuzzy closure spaces. In particular, two families \(F(S)\) and \(F(C)\) of fuzzy closure systems and fuzzy closure operators on \(X\) are complete lattice isomorphic.
Kim, Yong Chan, Ko, Jung Mi
openaire +2 more sources
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Maximal functions and subordination for operator groups. [PDF]
, 2002 Let E be a UMD Banach space and L a positive and self-adjoint operator in L^2 of Laplace type such that the imaginary powers L^{-it} form a C_0 group of exponential growth on L^p(E).
Blower, Gordon
core +4 more sources