Results 171 to 180 of about 14,588,697 (257)

Chimeric IL‐6/4R‐LL37 Engineered Macrophages Achieve Synchronized Inflammation Control and Antimicrobial Defence in Sepsis

Advanced Science, EarlyView.
Engineered macrophages programmed in situ by LNP‐delivered IL‐6/4 fusion and LL37 mRNAs simultaneously dampen cytokine storm, promote M2‐like repair, and enhance direct bacterial killing in sepsis. This combinatorial strategy restores T cell and macrophage function, lowers organ bacterial burden, and improves survival, highlighting a precision, host ...
Tianyang Jie, Zheyu Zhang, Hao Zhang, Linke Bian, Penglong Zheng, Sijia Zhou, Minqi Wang, Mingyu Qu, Yufei Wang, Xinhua Qu, Bing Yue   +10 more
wiley   +1 more source

Different low activated clotting time target anticoagulation protocols for patients during extracorporeal membrane oxygenation management: a retrospective cohort study. [PDF]

Front Med (Lausanne)
Gu F, Zhang M, Zhang Z, Zheng J, Jia L.
europepmc   +1 more source

An ex vivo comparison of partial thromboplastin time and activated clotting time for heparin anticoagulation in an ovine model. [PDF]

Artif Organs, 2022
Berk ZBK, Shah A, Sun W, Griffith BP, Wu ZJ.   +4 more
europepmc   +1 more source

Bioadhesive‐Integrated 3D‐Printed Multilayer Scaffolds Secure a Mechanically‐Stable Osteoimmune Niche for Enhanced Bone Augmentation

Advanced Science, EarlyView.
A 3D‑printed multilayer adhesive scaffold, firmly anchored to bone defects by simple finger pressing, suppresses micromotion and secures mechanical stability of the osteogenic niche. This stabilization likely contributes to the enhanced bone augmentation by fostering a pro‑regenerative mechano‐immune profile—characterized by M2‑like macrophage ...
Delu Zhao, Qiuyi Li, Lingyun Wang, Chongao Zhang, Yutian Cheng, Shuang Liu, Fulan Wei, Zheqin Dong   +7 more
wiley   +1 more source

Activated Clotting Time and Haemostatic Complications in Patients Receiving ECMO Support: A Systematic Review. [PDF]

J Cardiovasc Dev Dis
Schwaiger D, Schausberger L, Treml B, Jadzic D, Innerhofer N, Oberleitner C, Bukumirić Z, Spurnić I, Rajsic S.   +8 more
europepmc   +1 more source

Measuring Activated Clotting Time during Cardiac Catheterization and PCI: The Effect of the Sampling Site. [PDF]

J Interv Cardiol, 2021
Heemelaar JC, Berkhout T, Heestermans AACM, Zant JC, de Vos AMJ, Verouden NJW, Dirksen MT, van Ramshorst J.   +7 more
europepmc   +1 more source

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

Unmasking the phospholipid-induced "hook effect" and its implications - increasing phospholipid can also lead to a longer clotting time in coagulation assays. [PDF]

J Thromb Thrombolysis
Ling L, Liu C, Huang X, Wang S, Yu Z, Zhou J.   +5 more
europepmc   +1 more source

Effect of uninterrupted dabigatran or rivaroxaban on achieving ideal activated clotting time to heparin response during catheter ablation in patients with atrial fibrillation. [PDF]

J Geriatr Cardiol, 2022
Xin Q, Zhang C, Wang YJ, Li J, Chen T, Li SX, Wang W, Yang Y, Song WJ, Zhou J, Shi XM.   +10 more
europepmc   +1 more source

Regulating Cells Fate and Function to Facilitate Bone Regeneration via Designing Programmable Bio‐Interactive Materials

Advanced Science, EarlyView.
This article aims to elucidate the biological mechanisms of bone repair and the evolution of material design, highlighting key cellular and molecular processes. It further proposes strategies and prospects for programmable bio‐interactive materials, which enable precisely guided bone tissue regeneration by dynamically regulating cell behavior and the ...
Qingrui Fan, Fuming Cao, Junqiang Mao, Pengbin Yin, Licheng Zhang, Jianjun Wang, Peifu Tang   +6 more
wiley   +1 more source