Results 191 to 200 of about 14,588,697 (257)

Activated clotting time for anticoagulation management during catheter ablation of left atrial arrhythmias: Comparison of point-of-care devices in clinical routine. [PDF]

Heart Rhythm O2
Fülkell D, Koltzau A, Dinshaw L.
europepmc   +1 more source

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

Advanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang, Zijian Zhang, Fulin Dai, Zhijie Yin, Zhen Xing, Yurong Li, Haochong Lei, Junfeng Zhang, Chunyan Liu, Yan Li, Lei Dong   +10 more
wiley   +1 more source

Activated clotting time value as an independent predictor of postoperative bleeding and transfusion. [PDF]

Interdiscip Cardiovasc Thorac Surg
Pereira RM, Magueijo D, Guerra NC, Correia CJ, Rodrigues A, Nobre Â, Brito D, Moita LF, Velho TR.   +8 more
europepmc   +1 more source

SerpinA3 is an Endogenous TGF‐β Receptor Antagonist that Attenuates Cardiac Fibroblast Activation and Fibrotic Remodeling

Advanced Science, EarlyView.
SerpinA3 acts as an endogenous TGF‐β receptor antagonist that binds to the extracellular domain of TGFR‐1, thereby preventing TGFR‐1–TGFR‐2 complex formation. This receptor‐level blockade suppresses TGF‐β/Smad2/3 signaling, attenuates cardiac fibroblast activation, and extracellular matrix deposition, and ultimately alleviates pressure overload–induced
Hui Wang, Jieyu Cui, Chunlu Huang, Wanyi Guo, Tong Liu, Yi Zhu, Shuai Shao, Kangyin Chen, Jinlong He, Qiankun Bao   +9 more
wiley   +1 more source

Activated Clotting Time Requires Adaptation Across Altered Measurement Devices: Determination of Appropriate Range During Atrial Fibrillation Ablation. [PDF]

Clin Appl Thromb Hemost
Sakanoue H, Yamaji H, Okamoto S, Okano K, Fujita Y, Higashiya S, Murakami T, Hirohata S, Kusachi S.   +8 more
europepmc   +1 more source

Dual pKa Lipid Nanoparticles for Lung‐tropic mRNA Delivery and pH‐Programmed Endosomal Escape

Advanced Science, EarlyView.
Lipid nanoparticles’ bottleneck lies in low endosomal escape efficiency and liver‐dominant delivery after intravenous administration. To overcome these limitations, we present a stepwise pH‐programmed lipid nanoparticle system enabled by our newly synthesized ionizable lipid.
Seong Gi Lim, Minju Lee, Yiming Wang, Eunjin Choi, Ji Sun Park, Kyungmin Park, Hayoung Jeon, Donghyun Kim, Donghyun Lee, Yeeun Lee, Kee‐Pyo Kim, Eunha Kim, Heebeom Koo   +12 more
wiley   +1 more source

The Risk for Excessive Anticoagulation With Activated Clotting Time-Guided Monitoring in Patients Undergoing Transcatheter Aortic Valve Replacement. [PDF]

Struct Heart
Hokken TW, de Maat MPM, Van Mieghem NM.
europepmc   +1 more source

An RNA‐Binding Protein RBMS1 Promotes Endothelial Cell Autophagy to Maintain Vascular Homeostasis and Suppress Deep Vein Thrombosis

Advanced Science, EarlyView.
RBMS1, an RNA‐binding protein, restores vascular endothelial homeostasis by enhancing ATG3‐mediated autophagy, thereby attenuating thrombus formation and suggesting a potential avenue for further therapeutic exploration in DVT. ABSTRACT Deep vein thrombosis (DVT) is a prevalent vascular disorder characterized by aberrant coagulation within the deep ...
Chu Chu, Xinkui Liu, Nannan Fan, Xiaoyan Yu, Qiaoqiao Han, Yunhong Zhang, Wei Li, Yongqing Cai, Miaomiao Zhou, Fang Li, Feifei Shi, Zhen Zhang, Bin Wang, Xia Li   +13 more
wiley   +1 more source

Activated clotting time-guided heparinization during open AAA surgery: a pilot study. [PDF]

Pilot Feasibility Stud
Roosendaal LC, Hoebink M, Wiersema AM, Blankensteijn JD, Jongkind V.   +4 more
europepmc   +1 more source

Activated Clotting Time as a Marker of Inflammation in Hospitalized Patients. [PDF]

Clin Appl Thromb Hemost, 2020
Papageorgiou C, Synetos A, Tampakis K, Anninos H, Kontogiannis C, Kapelouzou A, Kanakakis I, Tousoulis D, Paraskevaidis I, Toutouzas K.   +9 more
europepmc   +1 more source