ABSTRACT Pharmacogenomics (PGx) is a rapidly evolving field that aims to personalize medicine by identifying genetic variations that influence drug response. While next‐generation sequencing (NGS)–based applications are not yet widely adopted in clinical routine, this study aimed to validate 9 genes of the NGS‐based Ion AmpliSeq Pharmacogenomics Panel ...
Yaowaluck Hongkaew +7 more
wiley +1 more source
Patient and Physician Perspectives on Pharmacotherapy in Parkinson's Disease Psychosis: A Mixed-Methods Exploratory Study. [PDF]
Rose O +5 more
europepmc +1 more source
Abstract Aims Ulotaront is an investigational trace amine‐associated receptor 1 (TAAR1) agonist demonstrated to slow gastric emptying in schizophrenia patients with metabolic syndrome (MetSyn) and prediabetes type 2. Here we evaluate the effects of ulotaront on glucose‐insulin dynamics in schizophrenia patients with MetSyn and prediabetes.
Snezana Milanovic +10 more
wiley +1 more source
ABSTRACT Background Fidelity assessments are crucial for ensuring evidence‐based delivery of first episode psychosis (FEP) services. The First Episode Psychosis Services Fidelity Scale (FEPS‐FS) is a validated tool for evaluating FEP programmes, but its application in Asian contexts remains unexplored.
Amelia Sim +6 more
wiley +1 more source
Stable monotherapy with clozapine or olanzapine increases the incidence of diabetes mellitus in people with schizophrenia [PDF]
S.S. Gill
openalex +1 more source
Elevated prolactin and association with treatment resistance indicators in first-hospitalized schizophrenia spectrum disorders: a real-world cohort study. [PDF]
Qi D +14 more
europepmc +1 more source
A meta-analysis of neuropsychological change to clozapine, olanzapine, quetiapine, and risperidone in schizophrenia [PDF]
Neil D. Woodward +3 more
openalex +1 more source
Striatal Nitric Oxide Activity Better Predicts Motor Disability Than Proto‐Oncogenes
The figure summarizes the experimental design in which mice received a single intraperitoneal injection of saline, haloperidol, metoclopramide, or L‐NOARG at different doses. Extrapyramidal (EPS) side effects were assessed using the catalepsy test and the Rota‐rod test.
Sonia Guerrero Prieto +3 more
wiley +1 more source
Clozapine (and norclozapine) concentrations are correlated with functioning, disability and side-effects when patients are treated with clozapine without the availability of therapeutic drug monitoring: A study of treatment-resistant schizophrenia inpatients. [PDF]
Petrovic V +4 more
europepmc +1 more source

