Results 211 to 220 of about 119,051 (375)

LL‐37 Inhibits TMPRSS2‐Mediated S2' Site Cleavage and SARS‐CoV‐2 Infection but Not Omicron Variants

open access: yesCell Proliferation, EarlyView.
Cathelicidin LL‐37 inhibits SARS‐CoV‐2 by blocking the catalytic activity of TMPRSS2. The N764K mutation in the spike S2 subunit of Omicron variants confers resistance to LL‐37‐induced inhibition of TMPRSS2‐mediated S2' priming. ABSTRACT Continual evolution of SARS‐CoV‐2 spike drives the emergence of Omicron variants that show increased spreading and ...
Zhenfei Bi   +10 more
wiley   +1 more source

ADENOVIRAL VECTOR TRANSFECTION INTO THE PULMONARY EPITHELIUM AFTER CECAL LIGATION AND PUNCTURE (CLP) IN RATS

open access: bronze, 1999
Yoram Weiss   +4 more
openalex   +1 more source

Posttranslational Control of ALA Synthesis Includes GluTR Degradation by Clp Protease and Stabilization by GluTR-Binding Protein1[OPEN]

open access: yesPlant Physiology, 2016
Janina Apitz   +6 more
semanticscholar   +1 more source

Bosutinib mitigates inflammation in experimental sepsis

open access: yesEuropean Journal of Clinical Investigation, EarlyView.
Abstract Background Sepsis, a leading cause of death globally, lacks targeted and effective treatment. Its pathophysiology involves unbalanced inflammation, marked by a high release of inflammatory mediators, leukocyte recruitment, vascular changes and dysfunction of the nervous and respiratory systems. Src family tyrosine kinases (SFK) play a critical
C. M. C. Cunha   +14 more
wiley   +1 more source

Does nature shape risk preferences? Evidence from Chile, Norway, and Tanzania

open access: yesEconomic Inquiry, Volume 63, Issue 2, Page 568-590, April 2025.
Abstract Does exposure to a more risky environment affect risk preferences? Going beyond single‐case study evidence, we report results from five surveys conducted in three countries and link this with administrative data to study whether a link between exposure and preferences is detectable and widespread. We find no evidence for endogenous preferences
Florian Diekert, Robbert‐Jan Schaap
wiley   +1 more source

FAHD1 and mitochondrial metabolism: a decade of pioneering discoveries

open access: yesThe FEBS Journal, EarlyView.
This paper reviews a decade of research on FAHD1, an important yet underappreciated enzyme in mitochondrial metabolism. FAHD1 plays a crucial role in energy production, oxidative stress regulation, and processes related to aging and overall health.
Elia Cappuccio   +9 more
wiley   +1 more source

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