Results 31 to 40 of about 31,869 (248)

CHITINASE-LIKE PROTEINS AS PROMISING MARKERS IN CANCER PATIENTS

open access: yesСибирский онкологический журнал, 2018
In the present review we collected the main studies regarding the role of chitinase-like proteins (CLPs), belonging to the family of Glyco_18 domain-containing proteins, in different cancers. In  humans, 3 chitinaselike proteins have been identified: YKL-
I. V. Larionova   +4 more
doaj   +1 more source

Compiling constraints in clp(FD)

open access: yesThe Journal of Logic Programming, 1996
Summary: We present the clp(FD) system: a constraint logic programming language with finite domain constraints. We detail its implementation, and present an abstract instruction set for the constraint solver that can be smoothly integrated into the WAM architecture.
Codognet, Philippe, Diaz, Daniel
openaire   +3 more sources

Molecular chaperones: Clamps for the Clps? [PDF]

open access: yesCurrent Biology, 1998
The Clp/Hsp100 molecular chaperones are unusual in their ability to tease apart protein aggregates and complexes. Recent results make a good case that these chaperones bind substrates via PDZ-like domains; this may reflect a general strategy for manipulating the] assembly state of substrate proteins.
Feng, Hwa-ping, Gierasch, Lila M
openaire   +2 more sources

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao   +6 more
wiley   +1 more source

Metabolic Labeling and Visualization of Isoprenoids Using Alkyne‐Modified DMAPP Analogs in Bacillus subtilis

open access: yesAngewandte Chemie, EarlyView.
Fluorescence‐based visualization and targeted mass–spectrometric enrichment of membrane‐embedded isoprenoids in Bacillus subtilis via cell‐permeant, alkynylated DMAPP analogs. ABSTRACT Isoprenoids are a chemically and functionally diverse class of metabolites that underlie essential bacterial physiology including respiration and cell envelope ...
Zackary N. Hulsey   +7 more
wiley   +2 more sources

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

open access: yesAdvanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong   +24 more
wiley   +1 more source

Surgical procedures to an experimental polymicrobial sepsis: Cecal Ligation and Puncture

open access: yesBrazilian Journal of Veterinary Pathology, 2008
Sepsis is still a leading cause of death worldwide and the mechanism of shock remains to be completely understood. Several studies have aimed to evaluate the effects of several drugs and procedures in sepsis, and the most common models of this study are ...
Gustavo B. Menezes   +3 more
doaj   +1 more source

Dual Cytoplasmic and Chloroplastic Mechanisms Fine‐Tune Chloroplast Division through ARC3 Protein Stability

open access: yesAdvanced Science, EarlyView.
ARC3 levels are controlled by cytosolic and chloroplast proteolytic systems. PUB52 mediates ARC3 precursor ubiquitination and degradation in the cytosol, while CLPC1 promotes ARC3 degradation in chloroplasts, where ARC2 protects ARC3 from excessive breakdown. Disrupting these components causes chloroplast division defects, placing them upstream of ARC3.
Yang Yuan   +5 more
wiley   +1 more source

Products of sequential CLP-compact spaces are CLP-compact

open access: yesAnnals of Pure and Applied Logic, 2006
The class of spaces which have the property that every cover by clopen sets has a finite subcover was introduced by A. Šostak under the name \textit{CB-compact}. These spaces are now known as \textit{CLP-compact} spaces and it has emerged that much of the interesting behaviour of this class derives from the possibility that the product of two ...
openaire   +2 more sources

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

open access: yesAdvanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li   +7 more
wiley   +1 more source

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