Results 61 to 70 of about 117,602 (361)
Evaluation of the Community Leadership Project 2.0 [PDF]
, 2014 Social Policy Research Associates (SPR), the contracted evaluator for CLP, began work partway through the first phase of CLP and has continued its role for CLP 2.0.
Castle Sinicrope +2 more
core
ClpS, a Substrate Modulator of the ClpAP Machine [PDF]
Molecular Cell, 2002 In the bacterial cytosol, ATP-dependent protein degradation is performed by several different chaperone-protease pairs, including ClpAP. The mechanism by which these machines specifically recognize substrates remains unclear. Here, we report the identification of a ClpA cofactor from Escherichia coli, ClpS, which directly influences the ClpAP machine ...
Dougan, David. +3 more
openaire +3 more sources
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
CLP projection for constraint handling rules [PDF]
Proceedings of the 13th international ACM SIGPLAN symposium on Principles and practices of declarative programming, 2011 This paper introduces and studies the notion of CLP projection for Constraint Handling Rules (CHR). The CLP projection consists of a naive translation of CHR programs into Constraint Logic Programs (CLP). We show that the CLP projection provides a safe operational and declarative approximation for CHR programs.
Haemmerlé, R. +2 more
openaire +3 more sources
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Angewandte Chemie, EarlyView.A pangenome analysis of the plant pathogen Pseudomonas syringae reveals two novel natural product families that facilitate niche adaptation. Comprehensive genomic and chemical analyses uncover unique biosynthetic gene clusters linked to host specificity and environmental fitness.
Shuaibing Zhang +7 more
wiley +2 more sources
An Investigation of Multi-Agent Planning in CLP [PDF]
Fundamenta Informaticae, 2010 This paper explores the use of Constraint Logic Programming (CLP) as a platform for experimenting with planning problems in the presence of multiple interacting agents. The paper develops a novel constraint-based action language, B MAP, that enables the declarative description of large classes of multi-agent and multi-valued domains.
DOVIER, Agostino +2 more
openaire +2 more sources
Stem cell research & therapeutics, 2015 IntroductionAn effective immune response to severe bacterial infections requires a robust production of the innate immunity cells from hematopoietic stem and progenitor cells (HSPCs) in a process called emergency myelopoiesis.
T. Skirecki +6 more
semanticscholar +1 more source
From Damage to Functionality: Remanufacturing of Thrust Roller Bearings by Tailored Forming
Advanced Engineering Materials, EarlyView.Herein, the wear and fatigue behavior of repaired bearing raceways with a new powder alloy is investigated using a FE8 test‐rig and an oscillating tribometer. The tests are compared with industrial manufactured bearings to evaluate the repair quality. The repair can extend the service life of the repaired bearing to that of a new bearing and improves ...
Felix Saure +3 more
wiley +1 more source
Helicenes with Four Helical Turns: Dimerization of [13]Helicenes to [27]Helicenoids
Angewandte Chemie, EarlyView.The telephone cord challenge: When a 2‐naphthol‐annulated hetero[13]helicene is oxidatively dimerized, two structurally distinct hetero[27]helicenes (both with four helical turns) are formed. When a racemic mixture of [13]helicenes is dimerized, a (M)‐ and a (P)‐helicene join to form a mixed [27]helicenoid (right), and when an enantiomerically pure [13]
Matea Sršen +4 more
wiley +2 more sources