Results 81 to 90 of about 30,356 (266)

Senkyunolide I Improves Septicemia‐Induced Brain Dysfunction via Regulating Nrf2 and Astrocyte Activity.

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Senkyunolide I (Sen I) has a protective effect on the blood–brain barrier (BBB) in rats with sepsis‐associated encephalopathy (SAE). This study investigated whether Sen I regulates Nrf2 to ameliorate sepsis‐induced brain dysfunction (SIBD). Sixty rats were randomly assigned into Sham group, SAE group (Model group), SAE + Sen I group (72 mg/kg,
Haohao Cao, Tao Liu, Meixia Xu
wiley   +1 more source

“FISIOLOGIA” À PORTUGUESA EM FOLHETIM

Revista de Estudos Literários, 2017
FISIOLOGIAS - Lopes de Mendonça  Introdução por Maria João ...
Maria João Simões
doaj   +1 more source

Prototyping CLP(FD) Tracers: a Trace Model and an Experimental Validation Environment [PDF]

arXiv, 2001
Developing and maintaining CLP programs requires visualization and explanation tools. However, existing tools are built in an ad hoc way. Therefore porting tools from one platform to another is very difficult. We have shown in previous work that, from a fine-grained execution trace, a number of interesting views about logic program executions could be ...
arxiv  

Paracetamol and its metabolites in children and adults with spinal muscular atrophy – a population pharmacokinetic model

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims The aim of the study was to investigate whether differences in paracetamol pharmacokinetics (PK) between spinal muscular atrophy (SMA) patients and healthy controls (HC) could be attributed to specific clinical covariates. Methods Nonlinear mixed‐effects modelling (NONMEM 7.4) was used to develop a population PK model, explore covariates ...
Qiaolin Zhao, Marie Mostue Naume, Brenda C. M. de Winter, Thomas Krag, Sissel Sundell Haslund‐Krog, Karoline Lolk Revsbech, John Vissing, Helle Holst, Morten Hylander Møller, Tessa Munkeboe Hornsyld, Morten Dunø, Christina Engel Hoei‐Hansen, Alfred Peter Born, Per Bo Jensen, Mette Cathrine Ørngreen   +14 more
wiley   +1 more source

LITERATURA NO SÉCULO XXI

Revista de Estudos Literários, 2012
O foco de atenção deste volume dirige-se para os aspetos tecnológicos e materiais que têm transformado as práticas de criação, comunicação e leitura literária, e cujos efeitos se fazem sentir transversalmente na cultura atual.
Manuel Portela
doaj   +1 more source

Optimized Mouse Model of Sepsis-Associated Encephalopathy: A Rational Standard Based on Modified SHIRPA Score and Neurobehaviors in Mice. [PDF]

CNS Neurosci Ther
This study focuses on the standardized establishment of animal models for sepsis‐associated encephalopathy (SAE). We employed a novel scoring method to identify mice with SAE, which may provide a potential theoretical foundation and research direction for future studies on SAE.
Xin Y, Tian M, Pei X, Deng S, Wang Y, Zhao F, Behnisch T, Gao Y, Gong Y.   +8 more
europepmc   +2 more sources

A Tribute to Alain Colmerauer [PDF]

arXiv, 2004
The paper describes the contributions of Alain Colmerauer to the areas of logic programs (LP) and constraint logic programs (CLP).
arxiv  

Degradation of Nonribosomal Peptide Synthetase Megasynthetases SrfAA and SrfAB by Acyldepsipeptide‐Activated ClpP in Bacillus Subtilis

ChemBioChem, EarlyView.
FtsZ is the only target protein that has been biochemically confirmed to be hydrolyzed both in vitro and in bacterial cells. Coupled with activity‐based protein profiling of nonribosomal peptide synthetases, the ClpP‐ADEP1 proteolytic complex that degrades the surfactin synthetases SrfAA and SrfAB in cell lysates and bacterial cells is demonstrated ...
Fumihiro Ishikawa, Chiharu Uchida, Rina Ohnishi, Taketo Imai, Genzoh Tanabe   +4 more
wiley   +1 more source

Recensão: ACTAS DO CONGRESSO RELIPES III — UNIVERSIDADE DA BEIRA INTERIOR, 18, 19 E 20 DE ABRIL 2007 — GABRIEL MAGALHÃES (ed.)

Revista de Estudos Literários, 2011
Recensão crítica de GABRIEL MAGALHÃES (ed.). ACTAS DO CONGRESSO RELIPES III – UNIVERSIDADE DA BEIRA INTERIOR, 18, 19 E 20 DE ABRIL DE 2007. Covilhã/Salamanca, UBI/Celya, 2007. 480 páginas. ISBN: 9788496482425.
Alberto Sismondini
doaj   +1 more source

Integrating Interval Constraints into Logic Programming [PDF]

arXiv, 2010
The CLP scheme uses Horn clauses and SLD resolution to generate multiple constraint satisfaction problems (CSPs). The possible CSPs include rational trees (giving Prolog) and numerical algorithms for solving linear equations and linear programs (giving CLP(R)). In this paper we develop a form of CSP for interval constraints.
arxiv