Results 81 to 90 of about 124,053 (354)

Early severe impairment of hematopoietic stem and progenitor cells from the bone marrow caused by CLP sepsis and endotoxemia in a humanized mice model

open access: yesStem cell research & therapeutics, 2015
IntroductionAn effective immune response to severe bacterial infections requires a robust production of the innate immunity cells from hematopoietic stem and progenitor cells (HSPCs) in a process called emergency myelopoiesis.
T. Skirecki   +6 more
semanticscholar   +1 more source

Meta-programming in CLP(R)

open access: yesThe Journal of Logic Programming, 1997
AbstractA widely used property of Prolog is that it is possible to write Prolog programs to construct and manipulate other Prolog programs in a very general manner. Unfortunately, this property is not carried over to richer languages such as CLP(R>)—the manipulation of CLP(R) programs in CLP(R) is quite limited. The reason is that the equality of terms
Spiro Michaylov   +3 more
openaire   +2 more sources

Risk management for traffic safety control [PDF]

open access: yes, 2002
This paper offers a range of modelling ideas and techniques from mathematical statistics appropriate for analysing traffic accident data for the East region operation of CLP Power Hong Kong Limited and for the Hong Kong population in general.
Luczak, M.J., Wylie, J.
core  

Critical Role of IL1R2‐ENO1 Interaction in Inhibiting Glycolysis‐Mediated Pyroptosis for Protection Against Lethal Sepsis

open access: yesAdvanced Science, EarlyView.
The authors have discovered that intracellular interleukin 1 receptor 2 (IL1R2) negatively regulates pyroptosis and inflammation by inhibiting glycolysis in sepsis. Soluble IL1R2 is released from macrophages undergoing pyroptosis. IL1R2 acts as a novel negative regulator of glycolysis by interacting with enolase 1 (ENO1), thereby inhibiting gasdermin D
Chuyi Tan   +13 more
wiley   +1 more source

The anti-inflammatory and antioxidant effects of Rosa damascena Mill. essential oil on the lung injury in the CLP model

open access: yesJournal of Medicinal Plants, 2020
Background: Sepsis or infection is the second leading cause of death in people who are intensive care units. Due to the side effects of NSAIDs drugs, the use of medicinal plants with anti-inflammatory such as Rosa (R.) damascene Mill.
Abolfazl Dadkhah   +6 more
doaj  

Origin of Circulating Free DNA in Sepsis: Analysis of the CLP Mouse Model

open access: yesMediators of Inflammation, 2015
Recently, it has been reported that circulating free DNA (cf-DNA) in the blood is increased in various infectious diseases, including sepsis. Moreover, a relationship between cf-DNA and neutrophil extracellular traps (NETs) has been suggested.
S. Hamaguchi   +6 more
semanticscholar   +1 more source

Economic modelling using constraint logic programming [PDF]

open access: yes, 1996
This paper investigates the use of constraint logic programming (CLP) in economic modelling through the design and implementation of two economic models.
Donovan, N, Gilbert, D
core  

Delayed wound repair in sepsis is associated with reduced local pro-inflammatory cytokine expression [PDF]

open access: yes, 2013
Sepsis is one of the main causes for morbidity and mortality in hospitalized patients. Moreover, sepsis associated complications involving impaired wound healing are common.
Albig, Michael   +7 more
core   +2 more sources

Calhm6 Governs Macrophage Polarization Through Chp1‐Camk4‐Creb1 Axis and Ectosomal Delivery in Inflammatory Responses

open access: yesAdvanced Science, EarlyView.
Calhm6 drives M2 macrophage polarization via the Chp1‐Camk4‐Creb1 axis, suppressing inflammation through calcium‐dependent ectosomal delivery. Calhm6 deficiency enhances M1 responses, boosting bactericidal activity but exacerbating tissue damage. LPS/IFNγ upregulate Calhm6 via Irf1, while IL‐4/Stat6 inhibits it, balancing immune outcomes.
Yanlong Xin   +14 more
wiley   +1 more source

Dexmedetomidine Ameliorate CLP-Induced Rat Intestinal Injury via Inhibition of Inflammation

open access: yesMediators of Inflammation, 2015
The aim was to verify that dexmedetomidine (DEX) can attenuate CLP-induced intestinal injury via inhibition of inflammation. Male Sprague-Dawley (SD) rats were randomly allocated into Sham group and the other three CLP model groups, in terms of different
Yan-qing Chen   +7 more
semanticscholar   +1 more source

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