Results 51 to 60 of about 129,580 (346)
Frontiers in Immunology, 2022 Severe mycoplasma pneumoniae pneumonia (MPP) in children presents with serious clinical complications. Without proper and prompt intervention, it could lead to deadly consequences.
Xi Chen +9 more
doaj +1 more source
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
International Journal of Infectious DiseasesObjectives: This study aimed to investigate the factors associated with the spontaneous clearance of Chlamydia trachomatis, a phenomenon that, despite a growing body of literature, remains understudied in the context of women in China.
Quan Zou +14 more
doaj +1 more source
Frontiers in Immunology, 2021 Immunotherapy has achieved positive clinical responses in various cancers. However, in advanced colorectal cancer (CRC), immunotherapy is challenging because of the deterioration of T-cell exhaustion, the mechanism of which is still unclear.
Jiaqi Hu +8 more
doaj +1 more source
Temporal Dynamics of Binocular Disparity Processing with Corticogeniculate Interactions [PDF]
, 1999 A neural model is developed to probe how corticogeniculate feedback may contribute to the dynamics of binocular vision. Feedforward and feedback interactions among retinal, lateral geniculate, and cortical simple and complex cells are used to simulate ...
Grossberg, Stephen, Grunewald, Alexander
core +1 more source
A Network of Portable, Low-Cost, X-Band Radars [PDF]
, 2012 Radar is a unique tool to get an overview on the weather situation, given its high spatio- temporal resolution. Over 60 years, researchers have been investigating ways for obtaining the best use of radar.
Allegretti, Marco +7 more
core +2 more sources
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Zombie cells hold clues to COPD progression [PDF]
Nature, 2020 Researchers are beginning to work out the part senescent cells play in the respiratory disease. Researchers are beginning to work out the part senescent cells play in the respiratory disease.
openaire +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source