Results 121 to 130 of about 10,963 (248)

Fully automated three‐dimensional deep learning‐based magnetic resonance imaging segmentation of brain cavities in epilepsy surgery

Epilepsia, EarlyView.
Abstract Objective There are several clinical and research applications for determining the amount of brain tissue resected after epilepsy surgery; however, manual segmentation of postoperative magnetic resonance imaging (MRI) is imprecise and time‐consuming.
Raphael Fernandes Casseb, Brunno Machado de Campos, Wallace Souza Loos, Marcelo Eduardo Ramos Barbosa, Marina Koutsodontis Machado Alvim, Gabriel Chagas Lutfala Paulino, Enrico Ghizoni, Francesco Pucci, Samuel Worrell, Clarissa Lin Yassuda, Roberto Medeiros de Souza, Lara Jehi, Fernando Cendes   +12 more
wiley   +1 more source

Biological age acceleration, genetic susceptibility, and incident diabetic retinopathy risk: A prospective cohort study. [PDF]

J Nutr Health Aging
Wang Y, Wang L.
europepmc   +1 more source

A translational multimodal machine‐learning prototype predicting valproate response in epilepsy treatment

Epilepsia, EarlyView.
Abstract Objective Epilepsy affects ~1% of the global population and often requires lifelong antiseizure medication (ASM) therapy. Valproic acid (VPA) is a commonly prescribed first‐line ASM, yet only approximately half of patients achieve sustained seizure freedom. Treatment selection remains largely empirical.
Simeon Platte, Afsheen Kumar, Giorgia Guerini, Massimo Pandolfo, Denise Haslinger, Colin B. Josephson, Guillermo Delgado‐García, Navprabhjot Kaur, Michaela‐Pauline Lux, Heiko Stempfle, Chantal Depondt, Reetta Kälviäinen, Felix Rosenow, Sophie von Brauchitsch, Karl Martin Klein, Andreas G. Chiocchetti   +15 more
wiley   +1 more source

Relevance of polymorphisms in TLR2/4 genes and their association with plasma cytokines for schizophrenia. [PDF]

Genes Immun
Patlola SR, Laighneach A, Morris DW, Hallahan B, McDonald C, Kelly JP, Donohoe G, McKernan DP.   +7 more
europepmc   +1 more source

Tonic–clonic seizures captured during ambulatory video‐EEG are frequently unreported

Epilepsia, EarlyView.
Abstract Objective Tonic–clonic seizures (TCSs) are widely regarded as clinically obvious, yet seizure counts used for treatment decisions and risk counseling often rely on patient or caregiver diaries. We sought to quantify the frequency of unreported TCSs during prolonged ambulatory video‐EEG (vEEG) monitoring and examined associations with ...
Ewan S. Nurse, Jacqueline French, Victoria Wong, Mark Cook   +3 more
wiley   +1 more source

Mendelian randomization study finds no causal link between inflammatory bowel disease and cirrhosis. [PDF]

Medicine (Baltimore)
An J, Zhu M, Fu Y, Gao K, Xie H, Ding H, Guo C, Zeng F, Xiong Y.   +8 more
europepmc   +1 more source

Magnetoencephalographic source imaging improves localization of the epileptogenic zone in multimodal imaging evaluation

Epilepsia, EarlyView.
Abstract Objective To assess the added diagnostic value of magnetoencephalographic source imaging (MSI) beyond conventional magnetic resonance imaging (MRI) and fluorodeoxyglucose–positron emission tomography (FDG‐PET) in localizing the epileptogenic zone, with stereo‐electroencephalography (SEEG) and surgical resection serving as reference standards ...
Romain Bouet, Marc Hermier, Karine Ostrowsky‐Coste, Sebastien Daligault, Sandrine Bouvard, Hélène Catenoix, Alexandra Montavont, Sébastien Boulogne, François Mauguière, Sylvain Rheims, Julien Jung   +10 more
wiley   +1 more source

Exploring Random Forest in Genetic Risk Score Construction. [PDF]

Genet Epidemiol
Venkat V, Clark K, Jeng XJ, Yao TC, Tsai HJ, Lu TP, Hsiao TH, Lin CH, Holloway S, Hoyo C, Chou SY, Wang H, Lee WP, Wang LS, Tzeng JY.   +14 more
europepmc   +1 more source

Does age influence diagnostic outcomes in an adult cohort referred to a first‐seizure clinic?

Epilepsia, EarlyView.
Abstract Objective The aging Danish population is associated with increasing morbidity and healthcare utilization. This study examines age‐related differences in resource utilization and diagnostic outcomes between older (65–95 years) and younger adults (18–64 years) evaluated for suspected epilepsy, including clinical management, diagnostic yield, and
Anne Line Lund Birkmose, Corinna Lackmann, Lars Hageman Pinborg, Kimmo Jensen   +3 more
wiley   +1 more source

Interpretable machine learning in type-2 diabetes prediction in patients with depressive symptoms: Insights from mendelian randomization and physical activity. [PDF]

Sci Prog
Li Z, Qiu X, Wu W, Kang H.
europepmc   +1 more source