Results 131 to 140 of about 10,963 (248)

Multi‐Cohort Analysis Reveals Genetic Predispositions to Clonal Hematopoiesis as Mutation‐Specific Risk Factors for Stroke

Advanced Genetics, Volume 6, Issue 1, March 2025.
This study comprehensively evaluated the differential effect of clonal hematopoiesis (CH) mutations on the risk of various stroke subtypes and functional recovery. It shows that TET2 is associated with small vessel stroke possibly via a pro‐inflammatory pathway. Abstract Recent observational studies have found an association between Clonal Hematopoesis
Shuyang Lin, Yang E. Li, Yan Wang
wiley   +1 more source

Genetic variants and polygenic risk scores associated with paroxysmal atrial fibrillation in the Japanese population. [PDF]

PLoS One
Shiomi M, Nagata Y, Sudo T, Takahashi K, Higuchi C, Ihara K, Asada K, Tanaka Y, Yamauchi Y, Sasaki T, Hachiya H, Imai Y, Fujita H, Sasano T, Furukawa T, Tanaka T.   +15 more
europepmc   +1 more source

New‐Onset Type 2 Diabetes Mellitus and Cancer Risk: A Matched Cohort Study in China Kadoorie Biobank

International Journal of Cancer, EarlyView.
ABSTRACT The prevalence of type 2 diabetes mellitus (T2DM) is rising rapidly in China and is linked to increased cancer risk, but causality remains unclear due to biases. We examined the causal effect of T2DM on cancer risk using bias‐minimizing methods.
Mengying Wang, Owen Tipping, Bowen Liu, Derrick A. Bennett, Baiyong Shen, Siyi Zou, Shulin Zhao, Richard M. Martin, Matthew Sperrin, Andrew G. Renehan   +9 more
wiley   +1 more source

Improved polygenic risk prediction for alzheimer's disease and related dementias using deep learning: age and APOE-stratified analysis. [PDF]

Alzheimers Res Ther
Mostafaei S, Shemer DW, Mak JKL, Karlsson IK, Hägg S.   +4 more
europepmc   +1 more source

Effects of washing procedures on cell loss in different diagnostic flow cytometry sample types

Cytometry Part B: Clinical Cytometry, EarlyView.
Gunnhild Vatne Leirvik, Trude Westgård, Mona Høysæter Fenstad, Henning Sørensen Øfsteng, Toril Holien   +4 more
wiley   +1 more source

The mitochondrial DNA copy number and ovary‐related reproductive disorders: A bidirectional two‐sample Mendelian randomization study

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 112-120, April 2025.
Abstract Objective In the present study, a bidirectional two‐sample Mendelian randomization approach was utilized to explore potential causal relationships between mitochondrial DNA copy number (mtDNA‐CN) and ovary‐related reproductive disorders (ORRDs), including ovarian dysfunction, ovarian cyst, polycystic ovary syndrome (PCOS), premature ovarian ...
Ke Peng, Xiao Han, Congquan Wu, Qiaowen Lu, Shujun Gao   +4 more
wiley   +1 more source

Eliminating viscosity challenges in continuous cultivation of yeast producing a GLP-1 like peptide. [PDF]

Microb Cell Fact
Voulgaris I, Nielsen AN, Petersen T, Jensen S.   +3 more
europepmc   +1 more source

Maternal and perinatal outcomes of pregnant women with echocardiographically high probability of pulmonary arterial hypertension

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study aimed to describe maternal and perinatal outcomes among pregnant women with echocardiographically high probability of pulmonary arterial hypertension (PAH) managed at a quaternary center and to compare outcomes between women with and without cardiac complications (CC).
Laura Belmont‐Rojo, Rosa Hernandez‐Cruz, Ana Jimena Lopez‐Diaz, Diana Yazmin Copado‐Mendoza, Tirso Rubalcava‐Rubalcava, Mario Isaac Lumbreras‐Marquez, Maria Antonia Pijuan‐Domenech   +6 more
wiley   +1 more source

Structure-aware retinal disentanglement reveals the genetic architecture of ocular and systemic diseases. [PDF]

PLOS Digit Health
Wei C, Zhang H, Huang R, Cai Z, Wu H, Zhong C, Zhang J, Yang X, Sun L, Wang X, Chen Z, Wu H, Liu Y, Tan H.   +13 more
europepmc   +1 more source

Implementation of home‐based telemonitoring and teleconsultations for obstetrics: A cross‐sectional survey of current practice in the United Kingdom

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective The requirement for regular maternal–fetal monitoring and clinical consultations has increased in recent years, placing a strain on obstetric services. In recent years, technology advancements have enabled the development of remote monitoring and teleconsultation strategies, aiming to provide care in the home setting.
Jack Le Vance, Leo Gurney, Victoria Hodgetts Morton, R. Katie Morris   +3 more
wiley   +1 more source