Results 111 to 120 of about 404,795 (397)

Screening versus routine practice in detection of atrial fibrillation in patients aged 65 or over: Screening versus routine practice in detection cluster randomised controlled trial [PDF]

, 2007
Objectives : To assess whether screening improves the detection of atrial fibrillation (cluster randomisation) and to compare systematic and opportunistic screening.
Allan, T.F., Bryan, S., Davies, M., Fitzmaurice, D.A., Hobbs, F.D.R., Holder, R.L., Jowett, S.M., Lip, G.Y.H., Mant, J.W.F., Murray, E.T., Raftery, J.P.   +10 more
core  

Cluster-randomised trial evaluating a complex intervention to improve mental health and well-being of employees working in hospital – a protocol for the SEEGEN trial

BMC Public Health, 2019
Health care employees in Germany and worldwide are exposed to a variety of stressors. However, most of the hospitals in Germany lack a systematic workplace health management. Thus, this study aims at the evaluation of the effects of a behavioural as well
Nadine Mulfinger, A. Sander, F. Stuber, Regina Brinster, F. Junne, R. Limprecht, M. Jarczok, T. Seifried-Dübon, M. Rieger, S. Zipfel, Martin Peters, M. Stiawa, I. Maatouk, Madeleine Helaß, C. Nikendei, E. Rothermund, N. Hander, U. Ziegenhain, Manuela Gulde, Melanie Genrich, B. Worringer, Janna Küllenberg, K. Blum, Stefan Süß, Elena Gesang, S. Ruhle, Anja Kirsten Marieke Antonia Lina Bernd Elena Lucia Mei Greinacher Bikowski Born Drews Hermeling Puschner , Anja Greinacher, Kirsten Bikowski, M. Born, Antonia Drews, L. Hermeling, B. Puschner, E. Tsarouha, L. Jerg-Bretzke, M. Kieser, A. Müller, Jochen Schweitzer-Rothers, P. Angerer, H. Gündel   +39 more
semanticscholar   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

TRial to Assess Implementation of New research in a primary care Setting (TRAINS): study protocol for a pragmatic cluster randomised controlled trial of an educational intervention to promote asthma prescription uptake in general practitioner practices

Trials, 2022
Background There is a marked increase in unscheduled care visits in school-aged children with asthma after returning to school in September. This is potentially associated with children not taking their asthma preventer medication during the school ...
Rami A. Alyami, Rebecca Simpson, Phillip Oliver, Steven A. Julious   +3 more
doaj   +1 more source

Preventing and lessening exacerbations of asthma in school-age children associated with a new term (PLEASANT) : Study protocol for a cluster randomised control trial [PDF]

, 2013
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work ...
Boote, Jonathan, Bradburn, Mike J., Cooper, Cindy L., Davis, Sarah, Elphick, Heather, Horspool, Michelle J., Julious, Steven A., Norman, Paul, Smithson, W. H., vanStaa, Tjeerd   +9 more
core   +4 more sources

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Community perspectives on randomisation and fairness in a cluster randomised controlled trial in Zambia

BMC Medical Ethics, 2019
Background One important ethical issue in randomised controlled trials (RCTs) is randomisation. Relatively little is known about how participating individuals and communities understand and perceive central aspects of randomisation such as equality ...
Maureen Mupeta Kombe, Joseph Mumba Zulu, Charles Michelo, Ingvild F. Sandøy   +3 more
doaj   +1 more source

Sustainable waiting time reductions after introducing the STAT model for access and triage: 12-month follow up of a stepped wedge cluster randomised controlled trial

BMC Health Services Research, 2020
Background Timely access is a challenge for providers of outpatient and community-based health services, as seen by the often lengthy waiting lists to manage demand.
Katherine E. Harding, David A. Snowdon, Luke Prendergast, Annie K. Lewis, Bridie Kent, Sandy F. Leggat, Nicholas F. Taylor   +6 more
doaj   +1 more source

Ethical issues in implementation research: a discussion of the problems in achieving informed consent [PDF]

, 2008
Background: Improved quality of care is a policy objective of health care systems around the world. Implementation research is the scientific study of methods to promote the systematic uptake of clinical research findings into routine clinical practice ...
A Iversen, A Vahratian, American Statistical Association, B Briesacher, B Woodward, C Junghans, C Verity, Council of the International Organisation of Medical Sciences, D Raffe, H Ward, International Statistical Institute, J Grimshaw, J Tu, Jane L Hutton, Jeremy M Grimshaw, JL Hutton, JL Hutton, L Doyal, M Eccles, M Eccles, M Eccles, M Robling, M Thompson, Martin P Eccles, MP Eccles, MRC ethics series, R Baker, R Foy, R Grol, R Winkelmann, RE Ashcroft, RE Ashcroft, Royal Statistical Society, S Blackstone, S Rogerson, S Woolf, SJL Edwards, T Beauchap, T Walley, World Medical Association Declaration of Helsinki   +39 more
core   +3 more sources

Effect of screening by clinical breast examination on breast cancer incidence and mortality after 20 years: prospective, cluster randomised controlled trial in Mumbai

British medical journal, 2020
Objective To test the efficacy of screening by clinical breast examination in downstaging breast cancer at diagnosis and in reducing mortality from the disease, when compared with no screening.
I. Mittra, G. Mishra, R. Dikshit, Subhadra Gupta, V. Kulkarni, H. Shaikh, S. Shastri, R. Hawaldar, Sudeep Gupta, C. Pramesh, R. Badwe   +10 more
semanticscholar   +1 more source