Results 171 to 180 of about 404,795 (397)

Reconciling research and implementation in micro health insurance experiments in India: study protocol for a randomized controlled trial

Trials, 2011
Background Microinsurance or Community-Based Health Insurance is a promising healthcare financing mechanism, which is increasingly applied to aid rural poor persons in low-income countries.
Doyle Conor, Panda Pradeep, Van de Poel Ellen, Radermacher Ralf, Dror David M   +4 more
doaj   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Cluster Randomised Trials

Journal of the Royal Statistical Society Series A: Statistics in Society, 2009
Richard J. Hayes, Lawrence H. Moulton
openaire   +2 more sources

A comprehensive evaluation of the impact of telemonitoring in patients with long-term conditions and social care needs: protocol for the whole systems demonstrator cluster randomised trial [PDF]

, 2011
Background: It is expected that increased demands on services will result from expanding numbers of older people with long-term conditions and social care needs.
Adam Steventon, Anne Rogers, Caroline Sanders, Catherine Henderson, Helen Doll, James Barlow, Jane Hendy, Martin Bardsley, Martin Cartwright, Martin Knapp, Peter Bower, Raymond Fitzpatrick, Shashivadan P Hirani, Stanton Newman   +13 more
core   +5 more sources

Protection by vaccination of children against typhoid fever with a Vi-tetanus toxoid conjugate vaccine in urban Bangladesh: a cluster-randomised trial

The Lancet, 2021
F. Qadri, F. Khanam, Xinxue Liu, K. Theiss-Nyland, P. K. Biswas, Amirul Islam Bhuiyan, Faisal Ahmmed, Rachel Colin-Jones, Nicola Smith, S. Tonks, M. Voysey, Y. Mujadidi, O. Mazur, N. Rajib, Md Ismail Hossen, Shamsher Ahmed, Arifuzzaman Khan, N. Rahman, Golap Babu, M. Greenland, Sarah Kelly, M. Ireen, K. Islam, P. O'Reilly, Karin Sofia Scherrer, V. Pitzer, K. Neuzil, K. Zaman, A. Pollard, J. Clemens   +29 more
semanticscholar   +1 more source

Mixed effects approach to the analysis of the stepped wedge cluster randomised trial—Investigating the confounding effect of time through simulation

PLoS ONE, 2018
Background A stepped wedge cluster randomised trial (SWCRT) is a multicentred study which allows an intervention to be rolled out at sites in a random order.
A. Nickless, M. Voysey, J. Geddes, Ly-Mee Yu, T. Fanshawe   +4 more
semanticscholar   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

CONSORT statement: extension to cluster randomised trials [PDF]

BMJ, 2004
Campbell, M, Elbourne, DR, Altman, D
openaire   +4 more sources

Randomised and non-randomised studies to estimate the effect of community-level public health interventions: definitions and methodological considerations

Emerging Themes in Epidemiology, 2017
Background The preferred method to evaluate public health interventions delivered at the level of whole communities is the cluster randomised trial (CRT).
Wolf-Peter Schmidt
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source