Results 11 to 20 of about 404,795 (397)

Cluster Randomised Trial

Japanese Journal of Biometrics
S. Oyamada, Yosuke Inaba
semanticscholar   +2 more sources

Cluster randomised trials [PDF]

Epidemiology and Psychiatric Sciences, 2011
Although randomised controlled trials are the reference methodology to assess the effects of therapeutic interventions, for interventions that naturally occur in groups of individuals random allocation of participants may be inappropriate. In these cases, the unit of random allocation may be the group or cluster, rather than the individual.
BARBUI, Corrado, CIPRIANI, Andrea
openaire   +4 more sources

Updated protocol of the SANO trial: a stepped-wedge cluster randomised trial comparing surgery with active surveillance after neoadjuvant chemoradiotherapy for oesophageal cancer

Trials, 2021
Background The Surgery As Needed for Oesophageal cancer (SANO) trial compares active surveillance with standard oesophagectomy for patients with a clinically complete response (cCR) to neoadjuvant chemoradiotherapy.
B. Eyck, B. J. van der Wilk, B. Noordman, B. Wijnhoven, S. Lagarde, H. Hartgrink, P. Coene, J. Dekker, M. Doukas, A. van der Gaast, J. Heisterkamp, E. Kouwenhoven, G. Nieuwenhuijzen, J. Pierie, C. Rosman, J. V. van Sandick, M. V. D. van der Sangen, M. Sosef, E. S. van der Zaag, M. Spaander, R. Valkema, Hester F. Lingsma, E. Steyerberg, J. V. van Lanschot   +23 more
semanticscholar   +1 more source

The impact of community-based integrated HIV and sexual and reproductive health services for youth on population-level HIV viral load and sexually transmitted infections in Zimbabwe: protocol for the CHIEDZA cluster-randomised trial

Wellcome Open Research, 2022
Background Youth have poorer HIV-related outcomes when compared to other age-groups. We describe the protocol for a cluster randomised trial (CRT) to evaluate the effectiveness of community-based, integrated HIV and sexual and reproductive health ...
C. Dziva Chikwari, E. Dauya, T. Bandason, M. Tembo, C. Mavodza, V. Simms, C. Mackworth-Young, T. Apollo, C. Grundy, H. Weiss, K. Kranzer, Tino Mavimba, Pitchaya P. Indravudh, A. Doyle, O. Mugurungi, A. Machiha, S. Bernays, J. Busza, B. Madzima, F. Terris-Prestholt, O. McCarthy, R. Hayes, Suzanna C. Francis, R. Ferrand   +23 more
semanticscholar   +1 more source

A cluster randomised trial of cookstove interventions to improve infant health in Ghana

BMJ Global Health, 2021
Introduction Household air pollution from solid fuel combustion for cooking and heating is a leading cause of childhood morbidity and mortality worldwide.
Darby Jack, K. Ae-Ngibise, Carlos F. Gould, E. Boamah-Kaali, Alison G. Lee, M. Mujtaba, S. Chillrud, S. Kaali, A. Quinn, S. Gyaase, Felix Boakye Oppong, D. Carrión, Oscar Agyei, Katrin Burkhart, J. A. Ana-Aro, Xinhua Liu, Y. Berko, B. Wylie, S. A. Etego, R. Whyatt, S. Owusu-Agyei, P. Kinney, Kwaku Asante   +22 more
semanticscholar   +1 more source

Digital adherence technologies to improve tuberculosis treatment outcomes in China: a cluster-randomised superiority trial

medRxiv, 2023
Background: Drug-sensitive tuberculosis treatment is for six months; adherence problems are common. Digital adherence technologies may improve outcomes.
Xiaoqiu Liu, Jennifer A Thompson, Haiyan Dong, S. Sweeney, Xue Li, Yanli Yuan, Xiao-Ming Wang, Wangrui He, B. Thomas, Caihong Xu, D. Hu, A. Vassall, S. Huan, Hui Zhang, Shi-wen Jiang, K. Fielding, Yanlin Zhao   +16 more
semanticscholar   +1 more source

Registry randomised trials: a methodological perspective

BMJ Open, 2023
Registry randomised clinical trials (RRCTs) have the potential to provide pragmatic answers to important clinical questions. RRCTs can be embedded into large population-based registries or smaller single site registries to provide timely answers at a ...
Christopher M Reid, Susannah Ahern, Ian Harris, Steven Y C Tong, Angela L Brennan, Dorota A Doherty, Carol Hodgson, Stephen McDonald, Jennifer Reilly, Jane Shrapnel, Charmaine S Tam, Leonie Wilcox, Anitha Balagurunathan, Belinda E Butcher   +13 more
doaj   +1 more source

Implementation of a batched stepped wedge trial evaluating a quality improvement intervention for surgical teams to reduce anastomotic leak after right colectomy

Trials, 2023
Background Large-scale quality improvement interventions demand robust trial designs with flexibility for delivery in different contexts, particularly during a pandemic.
Mary L. Venn, Charles H. Knowles, Elizabeth Li, James Glasbey, Dion G. Morton, Richard Hooper, ESCP EAGLE Safe Anastomosis Collaborative   +6 more
doaj   +1 more source

Effectiveness and cost-effectiveness of universal school-based mindfulness training compared with normal school provision in reducing risk of mental health problems and promoting well-being in adolescence: the MYRIAD cluster randomised controlled trial

Evidence-Based Mental Health, 2022
Background Systematic reviews suggest school-based mindfulness training (SBMT) shows promise in promoting student mental health. Objective The My Resilience in Adolescence (MYRIAD) Trial evaluated the effectiveness and cost-effectiveness of SBMT compared
W. Kuyken, S. Ball, C. Crane, Poushali Ganguli, Benjamin G. Jones, J. Montero-Marín, Elizabeth Nuthall, Anam Raja, L. Taylor, Kate Tudor, R. Viner, M. Allwood, L. Aukland, D. Dunning, Tríona Casey, Nicole Dalrymple, K. De Wilde, Eleanor-Rose Farley, J. Harper, N. Kappelmann, Mary Kempnich, Liz Lord, E. Medlicott, Lucy Palmer, Ariane Petit, A. Philips, Isobel Pryor-Nitsch, Lucy Radley, Anna Sonley, J. Shackleford, A. Tickell, S. Blakemore, The Myriad Team, O. Ukoumunne, M. Greenberg, T. Ford, T. Dalgleish, S. Byford, J. M. G. Williams   +38 more
semanticscholar   +1 more source

A study protocol for a cluster-randomised controlled trial of smartphone-activated first responders with ultraportable defibrillators in out-of-hospital cardiac arrest: The First Responder Shock Trial (FIRST)

Resuscitation Plus, 2023
Objective: To describe the First Responder Shock Trial (FIRST), which aims to determine whether equipping frequently responding, smartphone-activated (GoodSAM) first responders with an ultraportable AED can increase 30-day survival rates in OHCA. Methods:
Verity Todd, Bridget Dicker, Daniel Okyere, Karen Smith, Tony Smith, Graham Howie, Dion Stub, Michael Ray, Ralph Stewart, Tony Scott, Andy Swain, Natalie Heriot, Aroha Brett, Emily Mahony, Ziad Nehme   +14 more
doaj   +1 more source