Results 261 to 270 of about 404,795 (397)

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

Impact evaluation of a population-based 'Screen and Treat for Anaemia Reduction (STAR)' strategy: a cluster randomised trial in rural Telangana, India. [PDF]

BMJ Glob Health
Pullakhandam R, Augustine LF, Banjara SK, Dasi T, Palika R, Majumder R, Ghosh S, Sinha A, Kulkarni B.   +8 more
europepmc   +1 more source

Comparing dedicated and designated approaches to integrating task-shared psychological interventions into chronic disease care in South Africa: a three-arm, cluster randomised, multicentre, open-label trial

, 2022
Bronwyn Myers, Carl Lombard, Crick Lund, John A. Joska, Naomi Levitt, Tracey Naledi, Petal Petersen Williams, Claire van der Westhuizen, Pim Cuijpers, Dan J. Stein, Katherine Sorsdahl   +10 more
openalex   +2 more sources

Reduction of potentially inappropriate medication in the elderly: design of a cluster-randomised controlled trial in German primary care practices (RIME) [PDF]

, 2020
Ulrich Thiem, Stefan Wilm, Wolfgang Greiner, Henrik Rudolf, Hans J. Trampisch, Christiane Müller, Gudrun Theile, Petra Thürmann   +7 more
openalex   +1 more source

Effectiveness of polypill for primary and secondary prevention of cardiovascular diseases (PolyIran): a pragmatic, cluster-randomised trial

The Lancet, 2019
G. Roshandel, M. Khoshnia, H. Poustchi, K. Hemming, F. Kamangar, A. Gharavi, Mohammad R. Ostovaneh, A. Nateghi, M. Majed, Behrooz Navabakhsh, S. Merat, A. Pourshams, M. Nalini, F. Malekzadeh, Masoumeh Sadeghi, N. Mohammadifard, N. Sarrafzadegan, Mohammad Naemi-Tabiei, A. Fazel, P. Brennan, A. Etemadi, P. Boffetta, N. Thomas, T. Marshall, K. Cheng, R. Malekzadeh   +25 more
semanticscholar   +1 more source

Micropatterned Biphasic Printed Electrodes for High‐Fidelity on‐Skin Bioelectronics

Advanced Functional Materials, EarlyView.
Micropatterned biphasic printed electrodes achieve unprecedented skin conformity and low impedance by combining liquid‐metal droplets with microstructured 3D lattices. This scalable approach enables high‐fidelity detection of ECG, EMG, and EEG signals, including alpha rhythms from the forehead, with long‐term comfort and stability.
Manuel Reis Carneiro, Telmo Lopes, André F. Silva, Carmel Majidi, Mahmoud Tavakoli   +4 more
wiley   +1 more source

A Clinically Integrated Post-Graduate Training Programme in Evidence-Based Medicine versus ‘No Intervention’ for Improving Disability Evaluations: A Cluster Randomised Clinical Trial

, 2013
Rob Kok, Jan L. Hoving, Paul Smits, Sarah M. Ketelaar, F. J. H. van Dijk, Jos Verbeek   +5 more
openalex   +2 more sources

Bimetallic Nanoparticles as Cocatalysts for Photocatalytic Hydrogen Production

Advanced Functional Materials, EarlyView.
Recent developments have introduced bimetallic nanoparticles as effective cocatalysts for photocatalytic systems. This review explores the rapidly expanding research on bimetallic cocatalysts for photocatalytic production of hydrogen, emphasizing the creation of carrier‐selective contacts, localized surface plasmon resonance effects, methodologies for ...
Yufen Chen, Asier Agrelo‐Lestón, Ignasi Burgués‐Ceballos, Jordi Llorca, Lluís Soler   +4 more
wiley   +1 more source

The Influence of Annealing on the Sb Layer in the Synthesis of [001]‐Oriented Sb2Se3 Film for Photoelectrochemical Hydrogen Gas Generation

Advanced Functional Materials, EarlyView.
[001]‐oriented Sb2Se3 film with improved crystallinity and adjusted composition is achieved via a new thermal treatment approach consisting of preliminary annealing of the Sb layer before its selenization. The findings of this work demonstrate enhanced charge carriers' transportation, a stable performance, and an improvement of H2 generation from ...
Magno B. Costa, Moisés A. de Araújo, Joaquim Puigdollers, Pablo Ortega, Teresa Andreu, Cristobal Voz, Edgardo Saucedo, Lucia H. Mascaro   +7 more
wiley   +1 more source

The effects of implementing a point-of-care electronic template to prompt routine anxiety and depression screening in patients consulting for osteoarthritis (the Primary Care Osteoarthritis Trial): A cluster randomised trial in primary care

, 2017
Christian Mallen, Barbara I. Nicholl, Martyn Lewis, Bernadette Bartlam, Dan Green, Sue Jowett, Jesse Kigozi, John Belcher, Kris Clarkson, Zoe Lingard, C.F. Pope, Carolyn Chew‐Graham, Peter Croft, Elaine M. Hay, George Peat   +14 more
openalex   +2 more sources