Results 71 to 80 of about 175,554 (301)

[The CONSORT statement for cluster randomised trials].

Medicina clinica, 2011
With the publication of the CONSORT statement there is now increased awareness of the need to adequately report the findings of randomised controlled trials. The CONSORT statement includes a checklist of items that should be addressed in the trial report. The original CONSORT statement was developed to ensure the appropriate reporting of parallel group
Campbell, M, Elbourne, DR, Altman, D
openaire   +3 more sources

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

The reimagination of school-based physical activity research in the COVID-19 era.

PLoS Medicine, 2020
Deirdre Harrington and Michelle O'Reilly discuss the article "Effectiveness and cost-effectiveness of the GoActive intervention to increase physical activity among UK adolescents: A cluster randomised controlled trial" by Kirsten Corder and colleagues.
Deirdre M Harrington, Michelle O'Reilly
doaj   +1 more source

A cluster randomised control trial of a multi-component weight management programme for adults with intellectual disabilities and obesity [PDF]

, 2017
There have been few published controlled studies of multi-component weight management programmes that include an energy deficit diet (EDD), for adults with intellectual disabilities and obesity.
Boyle, Susan, Hankey, Catherine, Harris, Leanne, Jones, Nathalie, Melville, Craig, Murray, Heather, Pert, Carol, Tobin, Janet   +7 more
core   +1 more source

Improving management of obesity in primary care: cluster randomised trial [PDF]

BMJ, 2003
To evaluate a training programme intended to improve the management of obesity, delivered to general practice teams.Cluster randomised trial.Northern and Yorkshire region of England.44 general practices invited consecutively attending obese adults to participate; 843 patients attended for collection of baseline data and were subsequently randomised.4.5
Moore, H. J., Summerbell, C.D., Greenwood, D. C., Tovey, P., Griffiths, J., Henderson, M., Hesketh, K., Woolgar, S., Adamson, A.J.   +8 more
openaire   +5 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

School-based group interpersonal therapy for adolescents with depression in Nepal: protocol for a phase III realist cluster-randomised controlled trial

BMC Psychiatry
Background Depression is a leading cause of disability among adolescents, with the burden disproportionately affecting low- and middle-income countries (LMICs) where access to mental health care is limited.
Kelly Rose-Clarke, Cemile Ceren Sonmez, Sujan Shrestha, Bishnu Lamichhane, Indira Pradhan, Parbati Pandey, Pratima Kandel, John Hodsoll, Lauren Yan, Bryan Patenaude, Helen Verdeli, Kamal Gautam, Mark Jordans, Chris Bonell, Nagendra P. Luitel   +14 more
doaj   +1 more source

Protocol for the effective feedback to improve primary care prescribing safety (EFIPPS) study : a cluster randomised controlled trial using ePrescribing data [PDF]

, 2012
High-risk prescribing in primary care is common and causes considerable harm. Feedback interventions to improve care are attractive because they are relatively cheap to widely implement. There is good evidence that feedback has small to moderate effects,
Barnett, Karen, Bennie, Marion, Guthrie, Bruce, Petrie, Dennis, Ritchie, Lewis, Robertson, Chris, Treweek, S.   +6 more
core   +2 more sources

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Insecticide-treated nets for the prevention of malaria in pregnancy: a systematic review of randomised controlled trials.

PLoS Medicine, 2007
BackgroundProtection from malaria with insecticide-treated bednets (ITNs) during pregnancy is widely advocated, but evidence of benefit has been inconsistent.
Carol Gamble, Paul J Ekwaru, Paul Garner, Feiko O ter Kuile   +3 more
doaj   +1 more source