Results 111 to 120 of about 345,517 (350)

Dual-mobIlity verSus conventional Total hip arthroplasty In femoral Neck fractures, a registry-nested, open-label, Cluster-randomized crossover Trial (DISTINCT): statistical analysis plan

Bone & Joint Open
Aims: A statistical analysis plan for analysis of DISTINCT (Dual-mobIlity verSus conventional Total hip arthroplasty In femoral Neck fractures, a registry-nested, open-label, Cluster-randomized crossover Trial) is outlined to aid transparency in ...
The DISTINCT Study Group
doaj   +1 more source

Explaining temporal trends in annualized relapse rates in placebo groups of randomized controlled trials in relapsing multiple sclerosis: systematic review and meta-regression

, 2013
Background: Recent studies have shown a decrease in annualised relapse rates (ARRs) in placebo groups of randomised controlled trials (RCTs) in relapsing multiple sclerosis (RMS).
Friede, Tim, Nicholas, Richard, Röver, Christian, Schneider, Simon, Steinvorth, Simon M., Straube, Sebastian   +5 more
core   +1 more source

Blended home‐based exercise and dietary protein in community‐dwelling older adults: a cluster randomized controlled trial [PDF]

, 2020
Jantine van den Helder, Sumit Mehra, Carliene van Dronkelaar, Gerben ter Riet, Michael Tieland, Bart Visser, Ben Kröse, Raoul Engelbert, Peter J.M. Weijs   +8 more
openalex   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

A school-based intervention improved dietary intake outcomes and reduced waist circumference in adolescents: a cluster randomized controlled trial

Nutrition Journal, 2017
Background In Ecuador, adolescents’ food intake does not comply with guidelines for a healthy diet. Together with abdominal obesity adolescent’s inadequate diets are risk factors for non-communicable diseases.
Angélica Ochoa-Avilés, Roosmarijn Verstraeten, Lieven Huybregts, Susana Andrade, John Van Camp, Silvana Donoso, Patricia Liliana Ramírez, Carl Lachat, Lea Maes, Patrick Kolsteren   +9 more
doaj   +1 more source

Cost-effectiveness analysis of 3-D computerized tomography colonography versus optical colonoscopy for imaging symptomatic gastroenterology patients.

, 2013
BACKGROUND: When symptomatic gastroenterology patients have an indication for colonic imaging, clinicians have a choice between optical colonoscopy (OC) and computerized tomography colonography with three-dimensional reconstruction (3-D CTC).
A Briggs, A Graser, A Sweet, AI Neugut, B Bressler, B Bressler, B Hofstad, B Hofstad, BCSP Nhs, BP Mulhall, C Dukes, C Hassan, C Hassan, CD Johnson, D Burling, D Lee, DA Johnson, Department of Health and Human Services, DG Fryback, DH Kim, DJ Brenner, DK Rex, DK Rex, DK Rex, EC Obusez, F Loeve, HE Knoernschild, J Dowie, JA DiSario, James Bell, JJ Gonvers, L Ries, LM Almond, M Bose, M Chaparro, M Drummond, M McHugh, Manuel Gomes, ME Zalis, NICE, NICE, NICE, NM Gatto, Owen Epstein, P Consolo, P Tappenden, P Wylie, PB Cotton, Peter Wylie, PJ Pickhardt, PJ Pickhardt, PJ Pickhardt, PJ Pickhardt, PJ Pickhardt, PJ Pickhardt, PJ Pickhardt, RE Gelder Van, RE Schoen, RM Ness, Robert W. Aldridge, S Halligan, S Halligan, S Vijan, SJ Winawer, T Vanni, TR Levin, WS Atkin, WS Atkin   +67 more
core   +1 more source

Training contraceptive providers to offer intrauterine devices and implants in contraceptive care: a cluster randomized trial [PDF]

, 2018
Kirsten Thompson, Corinne H. Rocca, Lisa Stern, Johanna Morfesis, Suzan Goodman, Jody Steinauer, Cynthia C. Harper   +6 more
openalex   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Determining the impact of a new physiotherapist-led primary care model for back pain: protocol for a pilot cluster randomized controlled trial

Trials, 2017
Background Back pain is a leading contributor to disability, healthcare costs, and lost work. Family physicians are the most common first point of contact in the healthcare system for people with back pain, but physiotherapists (PTs) may be able to ...
Jordan Miller, David Barber, Catherine Donnelly, Simon French, Michael Green, Jonathan Hill, Joy MacDermid, Jacquelyn Marsh, Kathleen Norman, Julie Richardson, Monica Taljaard, Timothy Wideman, Lynn Cooper, Colleen McPhee   +13 more
doaj   +1 more source