Results 141 to 150 of about 345,517 (350)

Glymphatic Dysfunction Reflects Post‐Concussion Symptoms: Changes Within 1 Month and After 3 Months

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mild traumatic brain injury (mTBI) may alter glymphatic function; however, its progression and variability remain obscure. This study examined glymphatic function following mTBI within 1 month and after 3 months post‐injury to determine whether variations in glymphatic function are associated with post‐traumatic symptom severity ...
Eunkyung Kim   +3 more
wiley   +1 more source

Reporting quality of stepped wedge design randomized trials: a systematic review protocol

open access: yesClinical Epidemiology, 2016
Alex Thabane,1,2 Brittany B Dennis,3,4 Olga Gajic-Veljanoski,3,9,10 James Paul,2,3 Lehana Thabane2,3,5-8 1Life Sciences Program, Queen’s University, Kingston, ON, Canada; 2Department of Anesthesia, McMaster University Hamilton ON, 3Department of ...
Thabane A   +4 more
doaj  

Stepped-Wedge Trial of Decision Support for Acute Kidney Injury on Surgical Units

open access: yesKidney International Reports
Introduction: Acute kidney injury (AKI) is common in the perioperative setting and associated with poor outcomes. Whether clinical decision support improves early management and outcomes of AKI on surgical units is uncertain.
Matthew T. James   +10 more
doaj   +1 more source

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron   +5 more
wiley   +1 more source

Reasoning Exercises in Assisted Living: a cluster randomized trial to improve reasoning and everyday problem solving

open access: yesClinical Interventions in Aging, 2014
Kristine Williams,1 Ruth Herman,2 Daniel Bontempo3 1College of Nursing, University of Iowa, Iowa City, IA, USA; 2School of Nursing, University of Kansas Medical Center, Kansas City, KS, USA; 3The Schiefelbusch Institute for Life Span Studies, University
Williams K, Herman R, Bontempo D
doaj  

Long-Term Effects of a Comprehensive Intervention Strategy for Salt Reduction in China: Scale-Up of a Cluster Randomized Controlled Trial [PDF]

open access: gold
Min Liu   +15 more
openalex   +1 more source

Cutaneous Phosphorylated Alpha‐Synuclein in Lewy Body Dementia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the test performance of cutaneous phosphorylated alpha‐synuclein (P‐SYN) in dementia with Lewy bodies (DLB), individuals with reduced Montreal Cognitive Assessment (MoCA) and healthy controls. Methods This is the first subgroup analysis of the Synuclein‐One study, a prospective, blinded study evaluating P‐SYN detection ...
Christopher H. Gibbons   +31 more
wiley   +1 more source

Cluster minimal sufficient balance (CMSB): an efficient covariate balancing randomization method for cluster randomized trials

open access: yesBMC Medical Research Methodology
Background Cluster randomized trials (CRTs) require balanced baseline covariates to yield unbiased estimates of treatment effects. Existing approaches such as constrained randomization can improve balance but may compromise allocation randomness.
Jiaxin Cai   +9 more
doaj   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu   +10 more
wiley   +1 more source

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