Results 21 to 30 of about 1,520,474 (347)

Efficacy of a bivalent killed whole-cell cholera vaccine over five years: a re-analysis of a cluster-randomized trial

BMC Infectious Diseases, 2018
Background Oral cholera vaccine (OCV) is a feasible tool to prevent or mitigate cholera outbreaks. A better understanding of the vaccine’s efficacy among different age groups and how rapidly its protection wanes could help guide vaccination policy ...
Youyi Fong, M. Elizabeth Halloran, Jin Kyung Park, Florian Marks, John D. Clemens, Dennis L. Chao   +5 more
doaj   +1 more source

Collaborative care for depression in UK primary care: a randomized controlled trial [PDF]

, 2007
Reproduced with permission of the publisher. © 2008 Cambridge University Press.Background. Collaborative care is an effective intervention for depression which includes both organizational and patient-level intervention components.
A. Simpson, A. J. Lankshear, Cohen, D. Escott, D. Torgerson, D. A. Richards, J. Fletcher, K. Lovell, L. Gask, Lipsey, M. Barkham, M. Bland, Mann, Martell, none, none, none, P. Bower, Peveler, R. Richardson, S. Gilbody, S. Hennessy, Singleton, Spitzer, Ukoumunne, Ware, Wilkinson   +26 more
core   +1 more source

Ethical issues in cluster randomized trials conducted in low- and middle-income countries: an analysis of two case studies

Trials, 2020
Background Cluster randomized trials are common in health research in low- and middle-income countries raising issues that challenge interpretation of standard ethical guidelines.
Augustine T. Choko, Gholamreza Roshandel, Donaldson F. Conserve, Elizabeth L. Corbett, Katherine Fielding, Karla Hemming, Reza Malekzadeh, Charles Weijer   +7 more
doaj   +1 more source

Weight Loss in Underserved Patients - A Cluster-Randomized Trial.

New England Journal of Medicine, 2020
BACKGROUND Evidence of the effectiveness of treatment for obesity delivered in primary care settings in underserved populations is lacking. METHODS We conducted a cluster-randomized trial to test the effectiveness of a high-intensity, lifestyle-based ...
P. Katzmarzyk, Corby K. Martin, R. Newton, J. Apolzan, C. Arnold, T. Davis, E. Price-Haywood, Kara D Denstel, E. Mire, T. Thethi, P. Brantley, W. Johnson, V. Fonseca, J. Gugel, Kathleen B. Kennedy, C. Lavie, D. Sarpong, Benjamin F Springgate   +17 more
semanticscholar   +1 more source

Introduction of clinical guidelines for the diagnosis and treatment of osteoarthrosis: results of a cluster randomized trial

Научно-практическая ревматология, 2012
Objective: to evaluate the impact of the active introduction of clinical guidelines for the diagnosis and treatment of osteoarthrosis (OA) by primary care physicians on the efficiency of performed therapy and patient adherence to treatment. Methods. This
Dmitri Mikhailovich Maksimov, O M Lesnyak   +1 more
doaj   +1 more source

Design of trials for interrupting the transmission of endemic pathogens [PDF]

, 2016
Many interventions against infectious diseases have geographically diffuse effects. This leads to contamination between arms in cluster-randomized trials (CRTs).
Hiscox, Alexandra, Homan, Tobias, Maire, Nicolas, Mukabana, Richard, Silkey, Mariabeth, Smith, Thomas A., Takken, Willem   +6 more
core   +3 more sources

Reflection on modern methods: when is a stepped-wedge cluster randomized trial a good study design choice?

International Journal of Epidemiology, 2020
The stepped-wedge cluster randomized trial (SW-CRT) involves the sequential transition of clusters (such as hospitals, public health units or communities) from control to intervention conditions in a randomized order.
K. Hemming, M. Taljaard
semanticscholar   +1 more source

The mixed model for repeated measures for cluster randomized trials: a simulation study investigating bias and type I error with missing continuous data

Trials, 2020
Background Cluster randomized trials (CRTs) are a design used to test interventions where individual randomization is not appropriate. The mixed model for repeated measures (MMRM) is a popular choice for individually randomized trials with longitudinal ...
Melanie L. Bell, Brooke A. Rabe
doaj   +1 more source

Umbilical cord milking in non-vigorous infants: A cluster-randomized crossover trial.

American Journal of Obstetrics and Gynecology, 2022
BACKGROUND Delayed cord clamping (DCC) and umbilical cord milking (UCM) provide placental transfusion to vigorous newborns. Delayed cord clamping in non-vigorous newborns may not be provided due to perceived need for immediate resuscitation.
A. Katheria, E. Clark, Bradley K. Yoder, G. Schmölzer, B. H. Yan Law, W. el-Naggar, D. Rittenberg, Sheetal G Sheth, Mohamed Mohamed, Courtney B. Martin, F. Vora, S. Lakshminrusimha, M. Underwood, J. Mazela, J. Kaempf, M. Tomlinson, Y. Gollin, K. Fulford, Y. Goff, P. Wozniak, K. Baker, W. Rich, A. Morales, Michael W. Varner, D. Poeltler, Y. Vaucher, J. Mercer, N. Finer, L. El ghormli, M. Rice   +29 more
semanticscholar   +1 more source

Mass Azithromycin Distribution and Community Microbiome: A Cluster-Randomized Trial. [PDF]

, 2018
BackgroundMass distributions of oral azithromycin have long been used to eliminate trachoma, and they are now being proposed to reduce childhood mortality. The observed benefit appears to be augmented with each additional treatment, suggesting a possible
Amza, Anderson, Bhosai, Doan, Doan, Dobin, Fu, Grassly, Honda, Jost, Jost, Keenan, Kim, Kitzis, Knight, Langmead, Lukehart, Mai, McMullan, Mosca, Ogbo, Parker, Porco, See, Thaiss, UNICEF/WHO, Yassour, Young, Ziv   +28 more
core   +1 more source