Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez+5 more
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Identification of conserved and tissue-restricted transcriptional profiles for lipid associated macrophages. [PDF]
Xu Y+6 more
europepmc +1 more source
XLVI. A letter from Mr. John Ellis to Mr. Peter Collinson, F. R. S concerning cluster-polype, found in the sea near the coast of Greenland. [PDF]
John B. Ellis
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Inhibition of protein SUMOylation has been shown to block tumorigenesis; however, the specific mechanisms by which SUMOylation controls the tumor‐initiating capacities remain elusive. Li et al. describe the role of Etv1 SUMOylation in cancer stem cells using mouse models of mammary gland tumorigenesis.
Veronika Yevdokimova, Yannick D. Benoit
wiley +1 more source
Gaze cluster analysis reveals heterogeneity in attention allocation and predicts learning outcomes. [PDF]
John N+3 more
europepmc +1 more source
Photoelectric Studies. I. Color-Luminosity Array for Members of the Hyades Cluster.
O. J. Eggen
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On the Cluster Sets of Analytic Functions in a Jordan Domain. [PDF]
Makoto Ohtsuka
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This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima+6 more
wiley +1 more source
Cellular imbalance in proximal and distal lung of CFTR<sup>-/-</sup> sheep in utero and at birth. [PDF]
Leir SH+11 more
europepmc +1 more source
Understanding and measuring mechanical signals in the tumor stroma
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz+3 more
wiley +1 more source