Results 51 to 60 of about 2,076,484 (318)

Assessment of healthcare providers’ knowledge, attitude, and practice toward medical research in southwest Saudi Arabia: a cross-sectional study

BMC Medical Education
Background Medical research plays a crucial role in advancing the treatment and prevention of diseases, in addition to enhancing public health. Objectives This study aims to assess knowledge, attitude, and practice (KAP) of healthcare providers (HCPs) in
Hadi Al Sulayyim, Ali Alrashah, Ali Al Mansour, Fahad Al Sleem, Yahya Alfaifi, Mansour Alyami, Ali Alkhudeer, Hassan Al Hutaylah, Yousef Allajam, Abdullah Alkhurais, Noura Alfaifi, Mansour Majrshi, Abdullah Alsulayyim   +12 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Clustering with Same-Cluster Queries

CoRR, 2016
NIPS ...
Hassan Ashtiani, Shrinu Kushagra, Shai Ben-David   +2 more
openaire   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Cluster Haptic Texture Dataset: Haptic Texture Dataset with Varied Velocity-Direction Sliding Contacts

Scientific Data
Haptic sciences and technologies benefit greatly from comprehensive datasets that capture tactile stimuli under controlled, systematic conditions.
Michikuni Eguchi, Tomohiro Hayase, Yuichi Hiroi, Takefumi Hiraki   +3 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Ferroptosis triggers mitochondrial fragmentation via Drp1 activation

Cell Death and Disease
Constitutive mitochondrial dynamics ensure quality control and metabolic fitness of cells, and their dysregulation has been implicated in various human diseases.
Lohans Pedrera, Laura Prieto Clemente, Alina Dahlhaus, Sara Lotfipour Nasudivar, Sofya Tishina, Daniel Olmo González, Jenny Stroh, Fatma Isil Yapici, Randhwaj Pratap Singh, Nils Grotehans, Thomas Langer, Ana J. García-Sáez, Silvia von Karstedt   +12 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

A CLUE for CLUster ensembles

, 2005
Cluster ensembles are collections of individual solutions to a given clustering problem which are useful or necessary to consider in a wide range of applications.
Kurt Hornik, Hornik, Kurt
core   +1 more source