Results 71 to 80 of about 4,170,754 (298)

This Is Not a Myeloproliferative Neoplasm…

Pediatric Blood &Cancer, EarlyView.
Stephanie Juané Kennedy
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Monitoring of the Inner Ear Function During and After Cochlear Implant Insertion Using Electrocochleography

Trends in Hearing, 2019
To preserve residual hearing during cochlear implant (CI) surgery, it is desirable to use intraoperative monitoring of inner ear function (cochlear monitoring), especially during electrode insertion.
Sabine Haumann, Marina Imsiecke, Günther Bauernfeind, Andreas Büchner, Victor Helmstaedter, Thomas Lenarz, Rolf B. Salcher   +6 more
doaj   +1 more source

Estimating cluster-level local average treatment effects in cluster randomised trials with non-adherence [PDF]

, 2018
Non-adherence to assigned treatment is a common issue in cluster randomised trials (CRTs). In these settings, the efficacy estimand may be also of interest.
Agbla, Schadrac C., De Stavola, Bianca, DiazOrdaz, Karla   +2 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Propagation and Decay of Injected One-Off Delays on Clusters: A Case Study

, 2019
Analytic, first-principles performance modeling of distributed-memory applications is difficult due to a wide spectrum of random disturbances caused by the application and the system.
Afzal, Ayesha, Hager, Georg, Wellein, Gerhard   +2 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Genetic Testing Among Breast Cancer Patients in the Eastern Region of Saudi Arabia: Single-Center Experience

Journal of Epidemiology and Global Health
Background Genetic testing for persons with a heightened likelihood of harboring a germline mutation permits early identification and appropriate management.
Ghadeer Al Ghareeb, Zainab Al Nass, Salma Abu-Grain, Alia Alnaji, Hani Almohanna, Hadi Al Shaikh Nasser, Saad Al Shahrani   +6 more
doaj   +1 more source

Anatomy of $$\varepsilon '/\varepsilon $$ ε′/ε beyond the standard model

European Physical Journal C: Particles and Fields, 2019
We present for the first time a model-independent anatomy of the ratio $$\varepsilon '/\varepsilon $$ ε′/ε in the context of the $$\Delta S = 1$$ ΔS=1 effective theory with operators invariant under QCD and QED and in the context of the standard model ...
Jason Aebischer, Christoph Bobeth, Andrzej J. Buras, David M. Straub   +3 more
doaj   +1 more source

Clinical laboratory and dispersion pattern of COVID-19 in a family cluster in the social-distancing period

Journal of Infection in Developing Countries, 2020
Introduction: Since the first reports of coronavirus disease 2019 (COVID-19) in December 2019, the disease has spread worldwide. Different social isolation strategies have been adopted to reduce community transmission, but few studies have evaluated the
Carlos Alexandre Antunes de Brito, Marina Coelho Moraes de Brito, Thiago Henrique Fernandes Martins, Cecília Coelho Moraes de Brito, Maria Fátima Militão Albuquerque , Rita de Cássia Coelho Moraes de Brito   +5 more
doaj   +1 more source