Results 121 to 130 of about 22,633,303 (210)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Cluster analysis for personalised mobile entertainment content [PDF]
, 2010 There is much attention given to emerging technologies like mobile internet because of its increasing popularity. Much research has concentrated on hardware and some have focused on personalisation in terms of content visualisation.
Wong, K.W., Fung, C.C., Paireekreng, W.
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Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
A CLUE for CLUster Ensembles [PDF]
Cluster ensembles are collections of individual solutions to a given clustering problem which are useful or necessary to consider in a wide range of applications.
Kurt Hornik
core
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Cluster analysis methods for the study of sustainable tourism
openLa tesi analizza il turismo italiano con attenzione alla sostenibilità, integrando un quadro teorico con un’analisi empirica su 107 province e 24 indicatori economici, demografici, ambientali e turistici.
CASAGRANDE, PIETRO
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Farmer Acceptance of Genetically Modified seeds in Germany: Results of a Cluster Analysis [PDF]
Biotechnology, cluster analysis, German farmers, Agricultural and Food Policy, Crop Production/Industries, Farm Management, Food Security and Poverty, Q2,
Gyau, Amos +3 more
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Financing cluster initiatives [PDF]
In the last two decades hundreds of cluster initiatives have been launched involving virtually all regions of the world and their number is growing.
Skokan, Karel
core