Results 61 to 70 of about 27,265,132 (376)
Communications BiologyIn drug development, systematically characterizing a compound’s mechanism of action (MoA), including its direct targets and effector proteins, is crucial yet challenging.
Rina Kunishige +6 more
doaj +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Agricultural and Food Economics, 2023 Food insecurity is essential since its prevalence may hinder an individual or an economy from developing. The issue still lacks attention in Indonesia, as reflected in the lagging efforts to reduce food insecurity.
Dela Maria Ardianti +2 more
doaj +1 more source
, 2014 We present the results of a new analysis of the X-ray selected Active Galactic Nuclei (AGN) population in the vicinity of 135 of the most massive galaxy clusters in the redshift range of 0.2 < z < 0.9 observed with Chandra.
Allen, S. W. +8 more
core +1 more source
Predictive response-relevant clustering of expression data provides insights into disease processes [PDF]
, 2010 This article describes and illustrates a novel method of microarray data analysis that couples model-based clustering and binary classification to form clusters of ;response-relevant' genes; that is, genes that are informative when discriminating between
Abe +44 more
core +3 more sources
Clinical Chemistry, 1992 Abstract The purpose of this paper is to survey the usefulness of cluster analysis in the special case of diagnoses. This complex topic is restricted, however, to the application on laboratory characteristics, separately or in connection with clinical data.
W, Vogt, D, Nagel
openaire +2 more sources
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
, 2018 This paper argues that methods used for the classification and measurement of online education are not neutral and objective, but involved in the creation of the educational realities they claim to measure.
Carlo Perrotta, Ben Williamson
semanticscholar +1 more source
A Cluster Analysis of Insomnia [PDF]
Sleep, 1983 Data from three consecutive nights in the sleep laboratory and data from psychological questionnaires and interviews were cluster-analyzed. A total of 89 physician-referred insomniacs were included, together with 10 good sleepers. The goal was to develop a purely empirical classification scheme of insomnia and to compare it with the Association of ...
openaire +2 more sources
FEBS Letters, EarlyView.Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii +8 more
wiley +1 more source