Results 71 to 80 of about 27,265,132 (376)

Feature learning augmented with sampling and heuristics (FLASH) improves model performance and biomarker identification

npj Systems Biology and Applications
Big biological datasets, such as gene expression profiles, often contain redundant features that degrade model performance and limit generalization across independent datasets with complexities like class imbalance and hidden sub-clusters.
Shivam Kumar, Abhinav Agarwal, Samrat Chatterjee   +2 more
doaj   +1 more source

konnect2prot 2.0: Integrating advanced analytical tools for deeper understanding of protein properties in a functional protein-protein interaction network

Computational and Structural Biotechnology Journal
Proteins work in coordination to catalyze and regulate all biological activities and drive cellular functions. The collective behavior of proteins is studied through protein-protein interaction (PPI) networks, which provide a system-level understanding ...
Shivam Kumar, Abhinav Agarwal, Dipanka Tanu Sarmah, Samrat Chatterjee   +3 more
doaj   +1 more source

Understanding stakeholder values using cluster analysis [PDF]

, 2007
The K-Means and Ward’s Clustering procedures were used to categorize value similarities among respondents of a public land management survey. The clustering procedures resulted in two respondent groupings: an anthropocentrically focused group and an ...
Kaval, Pamela
core   +1 more source

Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes

FEBS Letters, EarlyView.
The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji, Yuko Katayama, Nanase Arata, Mariko Sasaki   +3 more
wiley   +1 more source

Use of Principal Component Analysis and Cluster Analysis for Differentiation of Traditionally-Manufactured Vinegars Based on Phenolic and Volatile Profiles, and Antioxidant Activity

Polish Journal of Food and Nutrition Sciences, 2020
This study aimed to characterize twelve vinegar samples produced by the traditional method with the use of whole fruits and without any preservatives in terms of their physicochemical properties, total phenolic content (TPC), total flavonoid content (TFC)
Ayse Karadag, Fatih Bozkurt, Hatice Bekiroglu, Osman Sagdic   +3 more
doaj   +1 more source

CLUMPP: a cluster matching and permutation program for dealing with label switching and multimodality in analysis of population structure

Bioinform., 2007
MOTIVATION Clustering of individuals into populations on the basis of multilocus genotypes is informative in a variety of settings. In population-genetic clustering algorithms, such as BAPS, STRUCTURE and TESS, individual multilocus genotypes are ...
M. Jakobsson, N. Rosenberg
semanticscholar   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Exploring the determinants of energy poverty in Indonesia’s households: empirical evidence from the 2015–2019 SUSENAS

Humanities & Social Sciences Communications
This study explores the determinants of household-level energy poverty in Indonesia by using highly granular, household-level socioeconomic data on Indonesia from the 2015–2019 National Socioeconomic Survey (SUSENAS).
Novani Karina Saputri, Lourentius Dimas Setyonugroho, Djoni Hartono   +2 more
doaj   +1 more source

The XMM Cluster Survey: X-ray analysis methodology [PDF]

, 2011
The XMM Cluster Survey (XCS) is a serendipitous search for galaxy clusters using all publicly available data in the XMM-Newton Science Archive. Its main aims are to measure cosmological parameters and trace the evolution of X-ray scaling relations.
A. Kathy Romer, Abazajian, Abbey, Abell, Adami, Adami, Allen, Alshino, Altieri, Anders, Andrew R. Liddle, Arabadjis, Arnaud, Arnaud, Arnaud, Arnaud, Arviset, Barkhouse, Ben Hoyle, Bertin, Bird, Blackburn, Blanton, Boyle, Bremer, Burenin, Burke, Böhringer, Böhringer, Cash, Cavaliere, Chris A. Collins, Christopher J. Miller, Collins, Craig D. Harrison, Croston, Cruddace, Cunha, Deponte Evans, Dickey, Doe, Dunkley, Dupke, Dupke, E. J. Lloyd-Davies, E. Naomi Dubois, Ebeling, Ebeling, Ebeling, Ebeling, Emma Kuwertz, Fassbender, Fassbender, Finoguenov, Finoguenov, Foley, Freeman, Frenk, Gabriel, Gastaldello, Ghizzardi, Ghizzardi, Gioia, Gioia, Gladders, Gobat, Gondoin, Gondoin, Gondoin, Gonzalez, Haberl, Hashimoto, Heather C. Campbell, Henry, Henry, Henry, Hilton, Hilton, Hilton, Horner, James, Jansen, John P. Stott, Jones, Kay, Kessler, Kivanc Sabirli, Koester, Kolokotronis, Lamer, Larson, Lloyd-Davies, Lumb, Majumdar, Mantz, Mantz, Mark Hosmer, Marriage, Martin Sahlén, Matt Hilton, Maughan, Maughan, Mehrtens, Melin, Menanteau, Mewe, Michael Davidson, Miller, Morrison, Mullis, Mullis, Mushotzky, Nicola Mehrtens, Olsen, Onuora, Oukbir, Pacaud, Papovich, Pedro T. P. Viana, Perlman, Peter Freeman, Piccinotti, Pierre, Ponman, Pradas, Pratt, Rapetti, Read, Read, Read, Reiprich, Robert C. Nichol, Robert G. Mann, Romer, Romer, Rosati, Rosati, Rozo, S. A. Stanford, Sahlén, Santos, Schneider, Schwope, Schwope, Scott T. Kay, Sehgal, Slezak, Stanford, Staniszewski, Stark, Stockman, Stott, Suhada, Suhada, Sunyaev, Tanaka, Vanderlinde, Vikhlinin, Vikhlinin, Villa, Voit, Véron-Cetty, Watson, Werner, Williamson, Wilms, Wilson, Wittman, Wolter, Wolter, Wu, Yu, Zwicky   +172 more
core   +2 more sources

Multimorbidity patterns with K-means nonhierarchical cluster analysis

BMC Family Practice, 2018
BackgroundThe purpose of this study was to ascertain multimorbidity patterns using a non-hierarchical cluster analysis in adult primary patients with multimorbidity attended in primary care centers in Catalonia.MethodsCross-sectional study using ...
C. Violán, A. Roso-Llorach, Q. Foguet-Boreu, Marina Guisado-Clavero, M. Pons-Vigués, E. Pujol-Ribera, J. Valderas   +6 more
semanticscholar   +1 more source