Results 101 to 110 of about 334,145 (360)

Effect of a differentiated service delivery model on virological failure in adolescents with HIV in Zimbabwe (Zvandiri): a cluster-randomised controlled trial.

Lancet Global Health, 2020
BACKGROUND Adolescents living with HIV face challenges to their wellbeing and antiretroviral therapy adherence and have poor treatment outcomes. We aimed to evaluate a peer-led differentiated service delivery intervention on HIV clinical and psychosocial
W. Mavhu, Nicola Willis, J. Mufuka, S. Bernays, M. Tshuma, C. Mangenah, H. Maheswaran, W. Mangezi, T. Apollo, R. Araya, H. Weiss, F. Cowan   +11 more
semanticscholar   +1 more source

Effect of a pharmacist intervention on asthma control. A cluster randomised trial [PDF]

Respiratory Medicine, 2013
Achievement and maintenance of good asthma control is a major objective in asthma management. However, asthma control in many patients is suboptimal, due to improper use of asthma medications and non-adherence. The aim of this study was to evaluate the effect of a pharmacist intervention on asthma control in adult patients.A 6-month cluster randomized ...
García-Cárdenas, Victoria, Sabater-Hernández, Daniel, Kenny, Patricia, Martínez-Martínez, Fernando, Faus, María José, Benrimoj, Shalom I.   +5 more
openaire   +2 more sources

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Feasibility of a cluster randomised trial on the effect of trauma life support training: a pilot study in India

BMJ Open
Objective To assess the feasibility of conducting a cluster randomised controlled trial comparing the effects of Advanced Trauma Life Support (ATLS) and Primary Trauma Care (PTC) with standard care on patient outcomes.Design This was a pilot pragmatic ...
Kapil Dev Soni, Nobhojit Roy, Martin Gerdin Wärnberg, Monty Khajanchi, Anurag Mishra, Catherine Juillard, Li Fellander-Tsai, Johanna Berg, Shamita Chatterjee, Geeta Ghag, Rajdeep Singh, Lovisa Strömmer, Debojit Basak, Tamal Khan, Vipul Versi Nandu   +14 more
doaj   +1 more source

Protocol for the effective feedback to improve primary care prescribing safety (EFIPPS) study : a cluster randomised controlled trial using ePrescribing data [PDF]

, 2012
High-risk prescribing in primary care is common and causes considerable harm. Feedback interventions to improve care are attractive because they are relatively cheap to widely implement. There is good evidence that feedback has small to moderate effects,
Barnett, Karen, Bennie, Marion, Guthrie, Bruce, Petrie, Dennis, Ritchie, Lewis, Robertson, Chris, Treweek, S.   +6 more
core   +2 more sources

Effectiveness of a brief group psychological intervention for women in a post-conflict setting in Pakistan: a single-blind, cluster, randomised controlled trial.

The Lancet, 2019
BACKGROUND Many women are affected by anxiety and depression after armed conflict in low-income and middle-income countries, yet few scalable options for their mental health care exist.
A. Rahman, Muhammad Naseem Khan, S. U. Hamdani, A. Chiumento, P. Akhtar, H. Nazir, A. Nisar, A. Masood, I. Din, Nasir Abbas Khan, R. Bryant, K. Dawson, M. Sijbrandij, Duolao Wang, M. Ommeren   +14 more
semanticscholar   +1 more source

Peer support for patients with type 2 diabetes: cluster randomised controlled trial [PDF]

BMJ, 2011
Objective To test the effectiveness of peer support for patients with type 2 diabetes. Design Cluster randomised controlled. Setting 20 general practices in the east of the Republic of Ireland. Participants 395 patients (192 in intervention group, 203 in control group) and 29 peer supporters with type 2 diabetes. Intervention All practices introduced a
Smith, S. M., Paul, G., Kelly, A., Whitford, D. L., O'Shea, E., O'Dowd, T.   +5 more
openaire   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Do regulatory tools instigate measures to prevent work-related psychosocial and ergonomic risk factors? A process evaluation of a Labour inspection authority trial in the Norwegian home-care services

BMC Research Notes, 2022
Objective There is a research gap regarding the way managers and employee representatives respond to Labour Authority interventions targeting work-related psychosocial and ergonomic risk factors.
Håkon A. Johannessen, Stein Knardahl, Jan S. Emberland, Øivind Skare, Bjørnar Finnanger Garshol   +4 more
doaj   +1 more source

Raising the standard of applied dementia care research : addressing the implementation error [PDF]

, 2014
Editoria
Moniz-Cook, Esme, Vernooij-Dassen, Myrra
core   +2 more sources