Results 161 to 170 of about 334,145 (360)

Protocol for the adolescent hayfever trial: cluster randomised controlled trial of an educational intervention for healthcare professionals for the management of school-age children with hayfever [PDF]

, 2010
Seasonal allergic rhinitis (hayfever) is common and can contribute to a considerable reduction in the quality of life of adolescents. This study aims to examine the effectiveness of standardised allergy training for healthcare professionals in improving ...
Victoria S Hammersley, Samantha Walker, Rob Elton, Aziz Sheikh   +3 more
core   +2 more sources

Integrating an early childhood development programme into Bangladeshi primary health-care services: an open-label, cluster-randomised controlled trial.

Lancet Global Health, 2019
BACKGROUND Poor development in young children in developing countries is a major problem. Child development experts are calling for interventions that aim to improve child development to be integrated into health services, but there are few robust ...
J. Hamadani, S. F. Mehrin, F. Tofail, M. I. Hasan, S. Huda, H. Baker-Henningham, D. Ridout, S. Grantham‐McGregor   +7 more
semanticscholar   +1 more source

Community involvement in dengue vector control: cluster randomised trial [PDF]

, 2010
Objective: To assess the effectiveness of an integrated community based environmental management strategy to control Aedes aegypti, the vector of dengue, compared with a routine strategy. Design Cluster randomised trial. Setting Guantanamo, Cuba. Participants 32 circumscriptions (around 2000 inhabitants each).
Vanlerberghe, V., Toledo, M. E., Rodriguez, M., Gómez, D., Baly, D., Baly, A., Benítez, J. R., Van der Stuyft, P.   +7 more
openaire  

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

An Occupational Therapy intervention for residents with stroke-related disabilities in UK Care Homes (OTCH): cluster randomised controlled trial with economic evaluation

Health Technology Assessment, 2016
Background: Care home residents with stroke-related disabilities have significant activity limitations. Phase II trial results suggested a potential benefit of occupational therapy (OT) in maintaining residents’ capacity to engage in functional activity.
Catherine M Sackley, Marion F Walker, Christopher R Burton, Caroline L Watkins, Jonathan Mant, Andrea K Roalfe, Keith Wheatley, Bart Sheehan, Leslie Sharp, Katie E Stant, Joanna Fletcher-Smith, Kerry Steel, Garry R Barton, Lisa Irvine, Guy Peryer, on behalf of the OTCH investigators   +15 more
doaj   +1 more source

Effects of the Learning Together intervention on bullying and aggression in English secondary schools (INCLUSIVE): a cluster randomised controlled trial

The Lancet, 2018
Summary Background Bullying, aggression, and violence among children and young people are some of the most consequential public mental health problems.
C. Bonell, E. Allen, E. Warren, Jennifer A. McGowan, L. Bevilacqua, F. Jamal, R. Legood, M. Wiggins, C. Opondo, A. Mathiot, J. Sturgess, A. Fletcher, Z. Sadique, D. Elbourne, D. Christie, L. Bond, Stephen Scott, R. Viner   +17 more
semanticscholar   +1 more source

Data processing in the DMagic cluster randomised controlled trial

The Lancet Diabetes & Endocrinology, 2022
Fottrell, Edward, King, Carina, Azad, Kishwar   +2 more
openaire   +3 more sources

Ethical issues in the design and conduct of cluster randomised controlled trials

BMJ, 1999
In most randomised controlled trials, individual patients are randomised to a treatment or control group, but sometimes this is undesirable or even impossible and groups (clusters) of people may be randomised instead. These are called cluster randomised controlled trials, and although they have been around for a long time, the need for them is likely ...
S J, Edwards, D A, Braunholtz, R J, Lilford, A J, Stevens   +3 more
openaire   +3 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Developing and testing accelerated partner therapy for partner notification for people with genital Chlamydia trachomatis diagnosed in primary care: a pilot randomised controlled trial [PDF]

, 2015
Background Accelerated partner therapy (APT) is a promising partner notification (PN) intervention in specialist sexual health clinic attenders. To address its applicability in primary care, we undertook a pilot randomised controlled trial (RCT) of two
Althaus, Andrew Copas, Anne M Johnson, Bailey, Cassell, Catherine H Mercer, Centers for Disease Control and Prevention, Chen, Claudia S Estcourt, Cowan, Estcourt, Estcourt, Ferreira, Greta Rait, Götz, Jackie A Cassell, Kazeem Aderogba, Laura Tickle, Lorna J Sutcliffe, Louise J Jackson, Low, Low, McCarney, McNulty, McNulty, McNulty, Mercer, Mercer, Mercer, Merle Symonds, Miller, Pamela Muniina, Roberts, Sarah Creighton, Shackleton, Tracy E Roberts, Turner   +36 more
core   +6 more sources