Baseline testing in cluster randomised controlled trials: should this be done? [PDF]
Background Comparisons of baseline covariates in randomised controlled trials whilst often undertaken is regarded by many as an exercise in futility.
Jaime E. Bolzern +2 more
doaj +5 more sources
Community-led trials: Intervention co-design in a cluster randomised controlled trial [PDF]
In conventional randomised controlled trials (RCTs), researchers design the interventions. In the Camino Verde trial, each intervention community designed its own programmes to prevent dengue.
Neil Andersson
doaj +3 more sources
Sample size calculations for cluster randomised controlled trials with a fixed number of clusters [PDF]
Background\ud Cluster randomised controlled trials (CRCTs) are frequently used in health service evaluation. Assuming an average cluster size, required sample sizes are readily computed for both binary and continuous outcomes, by estimating a design ...
A Donner +23 more
core +9 more sources
Cultural respect in general practice: a cluster randomised controlled trial [PDF]
To the Editor: We refer to Liaw and colleagues’1 recently published study in the Journal. We acknowledge the positive intentions and rigour of this trial, and empathically concur with Thompson and Thackrah's2 comment that the results of this research “[do] not mean that efforts to improve cultural competence in health care settings should be abandoned”.
Hickey, Sophie, West, Roianne
+11 more sources
Children overcoming picky eating (COPE) – A cluster randomised controlled trial [PDF]
Food neophobia limits dietary variety in children and adults. Interventions to alleviate the impact of neophobia on children's dietary variety have had varying success. The potential effectiveness of mindfulness, a process of bringing awareness to the present moment, has received little attention.
Bennett, Carmel +3 more
openaire +2 more sources
Community involvement in dengue vector control: cluster randomised trial [PDF]
To assess the effectiveness of an integrated community based environmental management strategy to control Aedes aegypti, the vector of dengue, compared with a routine strategy. Design Cluster randomised trial. Setting Guantanamo, Cuba. Participants 32 circumscriptions (around 2000 inhabitants each).
Vanlerberghe, V. +6 more
openaire +6 more sources
Community control strategies for scabies: A cluster randomised noninferiority trial
Background Scabies is a neglected tropical disease hyperendemic to many low- and middle-income countries. Scabies can be successfully controlled using mass drug administration (MDA) using 2 doses of ivermectin-based treatment. If effective, a strategy of 1-dose ivermectin-based MDA would have substantial advantages for implementing MDA for scabies at ...
Myra Hardy +13 more
openaire +5 more sources
Changing cluster composition in cluster randomised controlled trials: design and analysis considerations [PDF]
There are many methodological challenges in the conduct and analysis of cluster randomised controlled trials, but one that has received little attention is that of post-randomisation changes to cluster composition. To illustrate this, we focus on the issue of cluster merging, considering the impact on the design, analysis and interpretation of trial ...
Corrigan, Neil +3 more
openaire +3 more sources
Increasing child pedestrian and cyclist visibility: cluster randomised controlled trial [PDF]
Study objective: Visibility aids have the potential to reduce child pedestrian and cyclist injury but scarce data exist relating to their use or to interventions for increasing visibility aid use among children. This cluster randomised controlled trial was designed to assess the use of free visibility aids one and eight weeks after ...
C A, Mulvaney +3 more
openaire +2 more sources
Aims: The Prehospital Optimal Shock Energy for Defibrillation (POSED) study will assess the feasibility of conducting a cluster randomised controlled study of clinical effectiveness in UK ambulance services to identify the optimal shock energy for ...
Helen Pocock +9 more
doaj +1 more source

