Results 21 to 30 of about 334,145 (360)

Changing cluster composition in cluster randomised controlled trials: design and analysis considerations [PDF]

Trials, 2014
There are many methodological challenges in the conduct and analysis of cluster randomised controlled trials, but one that has received little attention is that of post-randomisation changes to cluster composition. To illustrate this, we focus on the issue of cluster merging, considering the impact on the design, analysis and interpretation of trial ...
Corrigan, Neil, Bankart, Michael J. G., Gray, Laura J., Smith, Karen L.   +3 more
openaire   +3 more sources

Implementation of the patient version of the evidence-based (S3) guideline for psychosocial interventions for patients with severe mental illness (IMPPETUS): study protocol for a cluster randomised controlled trial

Trials, 2020
Background The German guideline on psychosocial interventions for people with severe mental disorders recommends a broad spectrum of evidence-based treatments.
Johanna Breilmann, Reinhold Kilian, Steffi G. Riedel-Heller, Uta Gühne, Alkomiet Hasan, Peter Falkai, Andreas Allgöwer, Rainer Muche, Thomas Becker, Klemens Ajayi, Peter Brieger, Karel Frasch, Stephan Heres, Markus Jäger, Andreas Küthmann, Albert Putzhammer, Max Schmauß, Bertram Schneeweiß, Michael Schwarz, Markus Kösters   +19 more
doaj   +1 more source

The effect of a one-year vigorous physical activity intervention on fitness, cognitive performance and mental health in young adolescents: the Fit to Study cluster randomised controlled trial

International Journal of Behavioral Nutrition and Physical Activity, 2021
Background Physical activity (PA) may positively stimulate the brain, cognition and mental health during adolescence, a period of dynamic neurobiological development. High-intensity interval training (HIIT) or vigorous PA interventions are time-efficient,
T. Wassenaar, C. Wheatley, N. Beale, T. Nichols, P. Salvan, A. Meaney, K. Atherton, K. Diaz-Ordaz, H. Dawes, H. Johansen-Berg   +9 more
semanticscholar   +1 more source

Contamination in complex healthcare trials:the falls in care homes (FinCH) study experience [PDF]

, 2020
BACKGROUND: Trials are at risk of contamination bias which can occur when participants in the control group are inadvertently exposed to the intervention.
Allen, F, Darby, J, Fox, C, Gordon, A L, Horne, J C, Leighton, P, Logan, P A, Robinson, K, Sims, Erika   +8 more
core   +1 more source

Protocol for a parallel group, two-arm, superiority cluster randomised trial to evaluate a community-level complementary-food safety and hygiene and nutrition intervention in Mali: the MaaCiwara study (version 1.3; 10 November 2022)

Trials, 2023
Background Diarrhoeal disease remains a significant cause of morbidity and mortality among the under-fives in many low- and middle-income countries.
Evans A. Asamane, Laura Quinn, Samuel I. Watson, Richard J. Lilford, Karla Hemming, Cheick Sidibe, Ryan T. Rego, Sami Bensassi, Youssouf Diarra, Samba Diop, Om Prasad Gautam, Mohammad Sirajul Islam, Louise Jackson, Kate Jolly, Kassoum Kayentao, Ousmane Koita, Buba Manjang, Susan Tebbs, Nicola Gale, Paula Griffiths, Sandy Cairncross, Ousmane Toure, Semira Manaseki-Holland   +22 more
doaj   +1 more source

Pneumococcal conjugate vaccination schedules in infants—acquisition, immunogenicity, and pneumococcal conjugate and yellow fever vaccine co-administration study

Trials, 2022
Background Pneumococcal conjugate vaccines (PCVs) effectively prevent pneumococcal disease, but the global impact of pneumococcal vaccination is hampered by its cost.
Grant A. Mackenzie, Isaac Osei, Rasheed Salaudeen, Ousman Secka, Umberto D’Alessandro, Ed Clarke, Jonas Schmidt-Chanasit, Paul V. Licciardi, Cattram Nguyen, Brian Greenwood, Kim Mulholland   +10 more
doaj   +1 more source

Effectiveness of a medication adherence management intervention in a community pharmacy setting: a cluster randomised controlled trial

BMJ Quality & Safety, 2021
Background Non-adherence to medications continues to be a burden worldwide, with significant negative consequences. Community pharmacist interventions seem to be effective at improving medication adherence.
Andrea Torres-Robles, S. Benrimoj, M. A. Gastelurrutia, F. Martínez-Martínez, Tamara Peiro, B. Perez-Escamilla, K. Rogers, Isabel Valverde-Merino, R. Varas-Doval, V. García-Cárdenas   +9 more
semanticscholar   +1 more source

Increasing child pedestrian and cyclist visibility: cluster randomised controlled trial [PDF]

Journal of Epidemiology and Community Health, 2006
Study objective: Visibility aids have the potential to reduce child pedestrian and cyclist injury but scarce data exist relating to their use or to interventions for increasing visibility aid use among children. This cluster randomised controlled trial was designed to assess the use of free visibility aids one and eight weeks after ...
C A, Mulvaney, D, Kendrick, M C, Watson, C A C, Coupland   +3 more
openaire   +2 more sources

Exploring demographic and lifestyle associations with patient experience following telephone triage by a primary care doctor or nurse:secondary analyses from a cluster randomised controlled trial [PDF]

, 2015
The ESTEEM trial was a cluster randomised controlled trial that compared two telephone triage management systems (general practitioner (GP) or a nurse supported by computer decision support software) with usual care, in response to a request for same-day
Bunn, Campbell, Campbell, Campbell, Campbell, Kontopantelis, Lyratzopoulos, McKinstry, Mead, Murdoch, Murdoch, Paddison, Paddison, Richards, Richards, Salisbury, Stirewalt, van Uden, Warren   +18 more
core   +2 more sources

Effect of screening by clinical breast examination on breast cancer incidence and mortality after 20 years: prospective, cluster randomised controlled trial in Mumbai

British medical journal, 2020
Objective To test the efficacy of screening by clinical breast examination in downstaging breast cancer at diagnosis and in reducing mortality from the disease, when compared with no screening.
I. Mittra, G. Mishra, R. Dikshit, Subhadra Gupta, V. Kulkarni, H. Shaikh, S. Shastri, R. Hawaldar, Sudeep Gupta, C. Pramesh, R. Badwe   +10 more
semanticscholar   +1 more source