Results 141 to 150 of about 177,882 (303)

An empowerment programme to improve diet quality during pregnancy – the Power 4 a Healthy Pregnancy cluster randomised controlled trial

BMC Public Health
Background A healthy diet during pregnancy is vital for the well-being of both mothers and babies. However, navigating dietary choices amidst the unique psychological and physiological changes of pregnancy can be challenging.
Renske M. van Lonkhuijzen, Jeanne H. M. de Vries, Elske Brouwer-Brolsma, Susanne Cremers, Janine P. M. Faessen, Edith J. M. Feskens, Annemarie Wagemakers   +6 more
doaj   +1 more source

Prehospital optimal shock energy for defibrillation (POSED): A cluster randomised controlled feasibility trial

Resuscitation Plus
Background: We explored the feasibility of a large-scale UK ambulance services trial of optimal defibrillation shock energy for out-of-hospital cardiac arrest.
Helen Pocock, Charles D Deakin, Ranjit Lall, Felix Michelet, Chu Sun, Deb Smith, Catherine Hill, Jeskaran Rai, Kath Starr, Martina Brown, Isabel Rodriguez-Bachiller, Gavin D. Perkins   +11 more
doaj   +1 more source

CONSORT statement: extension to cluster randomised trials [PDF]

BMJ, 2004
Campbell, M, Elbourne, DR, Altman, D
openaire   +4 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Methods and baseline results of the Cohort of Health-Related Outcomes in Chronic Illness Care in General Practice in Denmark (CHRONIC-GP)

BMJ Open
Purpose The Cohort of Health-Related Outcomes in Chronic Illness Care in General Practice was established using data collected as part of a cluster-randomised trial.
Anne Holm, Anders Prior, Frans B Waldorff, Henrik HP Larsen, Tora G Willadsen, Anna B Lyhnebeck   +5 more
doaj   +1 more source

Trials randomised in clusters [PDF]

BMJ, 1997
J M. Bland, S. M Kerry
openaire   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Estimating cluster-level local average treatment effects in cluster randomised trials with non-adherence [PDF]

, 2018
Non-adherence to assigned treatment is a common issue in cluster randomised trials (CRTs). In these settings, the efficacy estimand may be also of interest.
Agbla, Schadrac C., De Stavola, Bianca, DiazOrdaz, Karla   +2 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Effects of primary or secondary prevention with vitamin A supplementation on clinically important outcomes: a systematic review of randomised clinical trials with meta-analysis and trial sequential analysis

BMJ Open
Objectives This systematic review with meta-analyses of randomised trials evaluated the preventive effects of vitamin A supplements versus placebo or no intervention on clinically important outcomes, in people of any age.Methods We searched different ...
Christian Gluud, Chavdar S Pavlov, Steven Kwasi Korang, Milica Bjelakovic, Goran Bjelakovic, Dimitrinka Nikolova, Naqash J Sethi   +6 more
doaj   +1 more source