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Cluster randomised controlled trials
2018A methodological guide from Cochrane Consumers and Communication about analysing cluster randomised controlled ...
Cochrane Consumers And Communication La Trobe University +2 more
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Cluster Randomised Controlled Trials
2008The unit of random allocation usually takes one of two forms: individual or cluster. In previous chapters we have considered randomised trials where individuals are randomised to one of the comparator groups. A cluster trial, sometimes known as a group or place randomised trial, randomises groups of individuals to the relevant trial arms.
David J. Torgerson, Carole J. Torgerson
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Cluster randomised controlled trials
BMJ, 2012Researchers investigated whether a systematic approach to the treatment of pain reduced agitation in people with moderate to severe dementia living in nursing homes. A cluster randomised controlled trial study design was used. The intervention comprised a stepwise protocol for the treatment of pain for eight weeks, with additional follow-up lasting ...
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Performing baseline testing in cluster randomised controlled trials
BMJ Evidence-Based Medicine, 2019Performing statistical tests of baseline characteristics is not usually advised for individually randomised trials. Should they be used for trials where participants are randomised in clusters? In the design of clinical trials, the most important techniques used for reducing bias are randomisation and blinding. Randomisation introduces an element of
Galal, U, Fanshawe, T
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Simulation in undergraduate paediatrics: a cluster‐randomised trial
The Clinical Teacher, 2015Summary Background Medical students lack confidence in recognising, assessing and managing unwell patients, particularly children. Our aim was to evaluate the impact of a 1‐day novel paediatric simulation course on medical students' ability to recognise and assess sick children, and to evaluate
Benita, Morrissey +4 more
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Treatment allocation in trials: cluster randomisation
BMJ, 2014Researchers investigated the effectiveness of neuromuscular training in reducing the rate of acute knee injuries in adolescent female football players. A cluster randomised controlled trial study design was used. The intervention was a 15 minute neuromuscular warm-up programme (targeting core stability, balance, and proper knee alignment) carried out ...
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Sample Size Calculations for Cluster Randomised Trials
Journal of Health Services Research & Policy, 2000Objectives: Cluster randomised trials, in which groups of individuals are randomised, are increasingly being used in the health field. Adopting a clustered approach has implications for the design of such trials, and sample size calculations need to be inflated to accommodate for the clustering effect.
Marion Campbell +2 more
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Cluster randomised controlled trials: sample size calculations
BMJ, 2013Researchers evaluated the effects of training primary care health professionals in counselling patients about health related behaviour change. A cluster randomised trial with general practices as the unit of randomisation was performed. The intervention consisted of behaviour change counselling in four risk behaviours (smoking, alcohol use, exercise ...
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Contamination effects in cluster randomised trials of TB interventions
The International Journal of Tuberculosis and Lung Disease<sec><title>BACKGROUND</title>Cluster randomised trials (CRTs) of TB interventions have achieved mixed results, with many lacking significant reductions in outcomes. Contamination in CRTs, resulting from short and long-term movement between clusters and the general population, may dilute the impact of measured intervention.</sec ...
K E, LeGrand +5 more
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