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Cluster-randomized trials: A closer look

Clinical Trials, 2016
Background: The cluster-randomized trial is the methodology of choice for evaluating interventions administered at the group level such as public health and healthcare quality improvement interventions. Because of unique features of this design, it can be difficult to apply standard research ethics guidelines to cluster-randomized trials.
Andrew D, McRae   +2 more
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Cluster Randomized Trials:Another Look

Hastings Center Report, 2013
The type of research known as cluster randomized trials raises ethical questions not readily answered within the standard understanding of research ethics. What distinguishes a CRT is that it randomizes at the level of social groups rather than at the level of individual research participants: in a CRT, the regimen under study might be assigned to a ...
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Cluster Randomized Clinical Trials

2017
This chapter discusses the design and analysis of cluster randomized clinical trials (CRCTs). These trials are useful when the intervention is most appropriately applied at a group level (e.g., provider, clinic, hospital). Since patients within a provider, clinic, or hospital are more likely to be similar than patients from another provider, clinic, or
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Cluster randomization trials

Statistical Methods in Medical Research, 2000
A. Donner, N. Klar
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Older adult participation in cancer clinical trials: A systematic review of barriers and interventions

Ca-A Cancer Journal for Clinicians, 2021
Mina S Sedrak   +2 more
exaly  

[The cluster-randomized trial].

Medecine sciences : M/S, 2004
Within the framework of a clinical trial, one is sometimes brought to randomize groups of subjects rather than the subjects themselves. This type of experimental design has methodological consequences of importance (in particular biostatistical consequences) and can limit the extrapolation of the results.
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Cluster Randomized Controlled Trials

2023
Dorothy V. M. Bishop, Paul A. Thompson
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An overview of precision oncology basket and umbrella trials for clinicians

Ca-A Cancer Journal for Clinicians, 2020
Kristian Thorlund, Edward J Mills
exaly  

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