Results 61 to 70 of about 262,646 (192)
Open Access Journal of Clinical Trials, 2013 Nicholas G Reich,1 Aaron M Milstone2,3 1Division of Biostatistics and Epidemiology, School of Public Health and Health Sciences, UMass-Amherst, Amherst, MA, USA; 2Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins ...
Reich NG, Milstone AM
doaj
Estimating cluster-level local average treatment effects in cluster randomised trials with non-adherence [PDF]
, 2018 Non-adherence to assigned treatment is a common issue in cluster randomised trials (CRTs). In these settings, the efficacy estimand may be also of interest.
Agbla, Schadrac C. +2 more
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A systematic review of school-based alcohol and other drug prevention programs [PDF]
, 2015 Background: Alcohol use in adolescents constitutes a major public health concern. Europe is the heaviest drinking region of the world. Several school-based alcohol prevention programs have been developed but it is not clear whether they are really ...
Agabio R +5 more
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Maximin Optimal Designs for Cluster Randomized Trials [PDF]
Biometrics, 2017 SummaryWe consider design issues for cluster randomized trials (CRTs) with a binary outcome where both unit costs and intraclass correlation coefficients (ICCs) in the two arms may be unequal. We first propose a design that maximizes cost efficiency (CE), defined as the ratio of the precision of the efficacy measure to the study cost.
Wu, Sheng +2 more
openaire +4 more sources
The effect of a postpartum IUD intervention on counseling and choice: Evidence from a cluster-randomized stepped-wedge trial in Sri Lanka [PDF]
, 2019 BACKGROUND: The International Federation of Gynaecology and Obstetrics (FIGO), in collaboration with the Sri Lankan College of Obstetrics and Gynaecologists (SLCOG), launched an initiative in 2014 to institutionalize immediate postpartum IUD (PPIUD ...
Canning, David +8 more
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Challenges of cluster randomized trials
Journal of Comparative Effectiveness Research, 2014 Cluster randomized trials are trials that randomize clusters of people, rather than individuals. They are becoming increasingly common. A number of innovations have been developed recently, particularly in the calculation of the required size of a cluster trial, the handling of missing data, designs to minimize recruitment bias, the ethics of cluster ...
openaire +2 more sources
Solving for the Indirect Human Subject in Cluster Randomised Trials
Voices in Bioethics, 2014 In 2012, a group of authors published a document entitled: The Ottawa Statement on Ethical Design & Conduct of Cluster Randomized Trials[1]. In this document, they posed and addressed six quandaries that face the implementation of cluster randomized ...
Marilyn Eshikena
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BMC Medical Research Methodology, 2004 Background Increasingly, researchers are recognizing that there are many situations where the use of a cluster randomized trial may be more appropriate than an individually randomized trial.
Grimshaw Jeremy M +2 more
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Case management for the treatment of patients with major depression in general practices – rationale, design and conduct of a cluster randomized controlled trial – PRoMPT (primary care monitoring for depressive patient's trial) [ISRCTN66386086] – Study protocol [PDF]
, 2005 Background: Depression is a disorder with high prevalence in primary health care and a significant burden of illness. The delivery of health care for depression, as well as other chronic illnesses, has been criticized for several reasons and new ...
Jochen Gensichen +34 more
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Journal of Statistical SoftwareMulti-period cluster randomized trials (CRTs) are increasingly used for the evaluation of interventions delivered at the group level. While generalized estimating equations (GEE) are commonly used to provide population-averaged inference in CRTs, there ...
Ying Zhang +4 more
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