Results 111 to 120 of about 324,788 (288)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Cluster and Principal Component Analyses of the Bioactive Compounds and Antioxidant Activity of Celery (Apium graveolens L.) Under Different Fertilization Schemes

open access: yesFoods
This research investigates the impact of various fertilization methods on the bioactive compound content and antioxidant activity of celery (Apium graveolens L.) root and leaf. Mineral fertilizer, poultry manure, cattle manure, sheep manure, supercompost,
Anita Milić   +9 more
doaj   +1 more source

Extension of the Cylindrical Root Model for Water Uptake to Non-Regular Root Distributions

open access: yesVadose Zone Journal, 2019
The water flow toward a single root is efficiently solved in cylindrical coordinates using the matrix flux potential. The upscaling of single root fluxes to whole root systems is commonly based on the assumption of regularly distributed and parallel ...
Jan Graefe   +2 more
doaj   +1 more source

New Acceleration of Nearly Optimal Univariate Polynomial Root-findERS

open access: yes, 2020
Univariate polynomial root-finding has been studied for four millennia and is still the subject of intensive research. Hundreds of efficient algorithms for this task have been proposed. Two of them are nearly optimal.
Pan, Victor Y.
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Corrigendum: Root Handling Affects Carboxylates Exudation and Phosphate Uptake of White Lupin Roots

open access: yesFrontiers in Plant Science, 2021
Raphael Tiziani   +5 more
doaj   +1 more source

The discovery of the church of Rungholt, a landmark for the drowned medieval landscapes of the Wadden Sea World Heritage

open access: yesScientific Reports
The UNESCO World Heritage Wadden Sea holds remains of a medieval cultural landscape shaped by interactions between man and natural forces. From the Netherlands to Denmark, human efforts of cultivating low-lying areas created a unique coastal landscape ...
Dennis Wilken   +12 more
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

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