Results 101 to 110 of about 2,836,700 (319)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Dianxin kexue, 2017 Virtual cell is identified as one of factors affecting the system performance in ultra-dense network where the interference is complex with the increasing density of cells and the resource allocation strategies of different dimensions were coupled in ...
Xiaoning ZHAO +2 more
doaj
Cluster cosmology without cluster finding
Monthly Notices of the Royal Astronomical SocietyABSTRACT We propose that observations of supermassive galaxies contain cosmological statistical constraining power similar to conventional cluster cosmology, and we provide promising indications that the associated systematic errors are comparably easier to control. We consider a fiducial spectroscopic and stellar mass complete sample of
Enia Xhakaj +7 more
openaire +2 more sources
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Nuove Prospettive Tecnologiche e di Servizio per l'Aerospazio
GEOmedia, 2018 Advances in technology have split the space community to focus on the miniaturization of conventional satellites, making smaller satellites increasingly popular every day and in recent years several small satellites have been launched (nano, micro and ...
Giovanni Nicolai
doaj
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Potential for Asia-Pacific Countries Innovative Development
Economic and Social Changes: Facts, Trends, Forecast, 2017 The relevance of the chosen topic is determined by the new geo-economic situation. Since the end of the 20th century, the vector of global economic development has shifted towards the Asia-Pacific region.
Kuznetsova Natalia V. +1 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Data Mining Application in Higher Learning Institutions
Informatics in Education, 2008 One of the biggest challenges that higher learning institutions face today is to improve the quality of managerial decisions. The managerial decision making process becomes more complex as the complexity of educational entities increase.
Naeimeh DELAVARI +2 more
doaj +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source