Results 121 to 130 of about 2,744,930 (320)
The cell clusters in the dorsal aorta of mammalian embryos [PDF]
Victor E. Emmel
openalex +1 more source
Cluster combinatorics of d-cluster categories
We study the cluster combinatorics of $d-$cluster tilting objects in $d-$cluster categories. By using mutations of maximal rigid objects in $d-$cluster categories which are defined similarly for $d-$cluster tilting objects, we prove the equivalences between $d-$cluster tilting objects, maximal rigid objects and complete rigid objects.
Bin Zhu, Yu Zhou
openaire +3 more sources
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Analysis of Application of Cluster Descriptions in Space of Characteristic Image Features
In this paper, we propose an investigation of the properties of structural image recognition methods in the cluster space of characteristic features. Recognition, which is based on key point descriptors like SIFT (Scale-invariant Feature Transform), SURF
Oleksii Gorokhovatskyi +2 more
doaj +1 more source
Note on a Moving Cluster of Stars of the Orion type in Perseus [PDF]
A. S. Eddinǵton
openalex +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source

