Results 141 to 150 of about 1,206,915 (318)
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Has political instability contributed to price clustering on Fiji's stock market? [PDF]
The goal of this paper is to examine evidence of stock price clustering on the South Pacific Stock Exchange, located in Fiji, and explore its determinants.
Paresh Kumar Narayan, Russell Smyth
core
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Journal of Biostatistics and Epidemiology, 2018 Background & Aim: Clustering is the method of classifying discrete data such as Kmodes, and Naïve Bayes classifier is the classification to predict the unknown real classes.
Zahra Zamaninasab +2 more
doaj
Supervised sampling for clustering large data sets [PDF]
, 2010 The problem of clustering large data sets has attracted a lot of current research. The approaches taken are mainly based either on the more efficient implementation or modification of existing methods or/and on the construction of clusters from a ...
Kosmidis, Ioannis, Karlis, Dimitris
core
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Clustering in an Object-Oriented Environment
This paper describes the incorporation of seven stand-alone clustering programs into S-PLUS, where they can now be used in a much more flexible way.
Mia Hubert, Peter Rousseeuw, Anja Struyf
core
Consistent parameter clustering: definition and analysis.
, 2007 Parameter clustering is a popular robust estimation technique based on location statistics in a parameter space where parameter samples are obtained from data samples.
Hillenbrand, Ulrich, Ulrich Hillenbrand
core
Multiorder neurons for evolutionary higher-order clustering and growth
, 2007 This letter proposes to use multiorder neurons for clustering irregularly shaped data arrangements. Multiorder neurons are an evolutionary extension of the use of higher-order neurons in clustering.
GUAN, Sheng Uei +5 more
core +1 more source